Concentration of perrhenate and pertechnetate solutions
Abstract
A method of preparing a concentrated solution of a carrier-free radioisotope which includes the steps of: a. providing a generator column loaded with a composition containing a parent radioisotope; b. eluting the generator column with an eluent solution which includes a salt of a weak acid to elute a target daughter radioisotope from the generator column in a first eluate. c. eluting a cation-exchange column with the first eluate to exchange cations of the salt for hydrogen ions and to elute the target daughter radioisotope and a weak acid in a second eluate; d. eluting an anion-exchange column with the second eluate to trap and concentrate the target daughter radioisotope and to elute the weak acid solution therefrom; and e. eluting the concentrated target daughter radioisotope from the anion-exchange column with a saline solution.
- Inventors:
-
- Oak Ridge, TN
- Clinton, TN
- Knoxville, TN
- Bonn, DE
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 871426
- Patent Number(s):
- 5729821
- Assignee:
- Lockheed Martin Energy Research Coirporation (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
H - ELECTRICITY H05 - ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR H05H - PLASMA TECHNIQUE
- DOE Contract Number:
- AC05-96OR22464
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- concentration; perrhenate; pertechnetate; solutions; method; preparing; concentrated; solution; carrier-free; radioisotope; steps; providing; generator; column; loaded; composition; containing; parent; eluting; eluent; salt; weak; acid; elute; target; daughter; eluate; cation-exchange; exchange; cations; hydrogen; anion-exchange; trap; concentrate; therefrom; saline; concentrated solution; saline solution; exchange column; acid solution; composition containing; ion-exchange column; weak acid; carrier-free radioisotope; column loaded; anion-exchange column; /423/250/424/
Citation Formats
Knapp, Furn F, Beets, Arnold L, Mirzadeh, Saed, and Guhlke, Stefan. Concentration of perrhenate and pertechnetate solutions. United States: N. p., 1998.
Web.
Knapp, Furn F, Beets, Arnold L, Mirzadeh, Saed, & Guhlke, Stefan. Concentration of perrhenate and pertechnetate solutions. United States.
Knapp, Furn F, Beets, Arnold L, Mirzadeh, Saed, and Guhlke, Stefan. Tue .
"Concentration of perrhenate and pertechnetate solutions". United States. https://www.osti.gov/servlets/purl/871426.
@article{osti_871426,
title = {Concentration of perrhenate and pertechnetate solutions},
author = {Knapp, Furn F and Beets, Arnold L and Mirzadeh, Saed and Guhlke, Stefan},
abstractNote = {A method of preparing a concentrated solution of a carrier-free radioisotope which includes the steps of: a. providing a generator column loaded with a composition containing a parent radioisotope; b. eluting the generator column with an eluent solution which includes a salt of a weak acid to elute a target daughter radioisotope from the generator column in a first eluate. c. eluting a cation-exchange column with the first eluate to exchange cations of the salt for hydrogen ions and to elute the target daughter radioisotope and a weak acid in a second eluate; d. eluting an anion-exchange column with the second eluate to trap and concentrate the target daughter radioisotope and to elute the weak acid solution therefrom; and e. eluting the concentrated target daughter radioisotope from the anion-exchange column with a saline solution.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 17 00:00:00 EST 1998},
month = {Tue Mar 17 00:00:00 EST 1998}
}
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Works referenced in this record:
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journal, January 1993
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Extending the life of a 99Tcm generator: a simple and convenient method for concentrating generator eluate for clinical use
journal, January 1993
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Highly concentrated [99mTc]pertechnetate solutions from (n,γ)99Mo/99mTc generators for nuclear medical use
journal, May 1994
- Seifert, Sepp; Wagner, Gerhard; Eckardt, Armin
- Applied Radiation and Isotopes, Vol. 45, Issue 5