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Title: Synthetic biochemistry molecular purge valve module that maintain co-factor balance

Abstract

The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.

Inventors:
; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771578
Patent Number(s):
10822623
Application Number:
16/243,332
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
DOE Contract Number:  
FC02-02ER63421
Resource Type:
Patent
Resource Relation:
Patent File Date: 01/09/2019
Country of Publication:
United States
Language:
English

Citation Formats

Bowie, James U., Opgenorth, Paul H., and Korman, Tyler P. Synthetic biochemistry molecular purge valve module that maintain co-factor balance. United States: N. p., 2020. Web.
Bowie, James U., Opgenorth, Paul H., & Korman, Tyler P. Synthetic biochemistry molecular purge valve module that maintain co-factor balance. United States.
Bowie, James U., Opgenorth, Paul H., and Korman, Tyler P. Tue . "Synthetic biochemistry molecular purge valve module that maintain co-factor balance". United States. https://www.osti.gov/servlets/purl/1771578.
@article{osti_1771578,
title = {Synthetic biochemistry molecular purge valve module that maintain co-factor balance},
author = {Bowie, James U. and Opgenorth, Paul H. and Korman, Tyler P.},
abstractNote = {The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {11}
}

Works referenced in this record:

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journal, July 2006


Metabolic Engineering of Escherichia coli: Increase of NADH Availability by Overexpressing an NAD+-Dependent Formate Dehydrogenase
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A synthetic biochemistry molecular purge valve module that maintains redox balance
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A synthetic biochemistry module for production of bio-based chemicals from glucose
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Synthetic biochemistry molecular purge valve module that maintain co-factor balance
patent, February 2019


A synthetic biochemistry platform for cell free production of monoterpenes from glucose
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Redox driven metabolic tuning: Carbon source and aeration affect synthesis of poly(3-hydroxybutyrate) in Escherichia coli
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Escherichia coli Malic Enzymes: Two Isoforms with Substantial Differences in Kinetic Properties, Metabolic Regulation, and Structure
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A molecular rheostat maintains ATP levels to drive a synthetic biochemistry system
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Enzyme-catalyzed poly(3-hydroxybutyrate) synthesis from acetate with CoA recycling and NADPH regeneration in Vitro
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