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Title: Synthetic biochemistry molecular purge valve module that maintain co-factor balance

Abstract

The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.

Inventors:
; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1502469
Patent Number(s):
10196653
Application Number:
15/127,351
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
DOE Contract Number:  
FC02-02ER63421
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Apr 02
Country of Publication:
United States
Language:
English

Citation Formats

Bowie, James U., Opgenorth, Paul H., and Korman, Tyler P.. Synthetic biochemistry molecular purge valve module that maintain co-factor balance. United States: N. p., 2019. Web.
Bowie, James U., Opgenorth, Paul H., & Korman, Tyler P.. Synthetic biochemistry molecular purge valve module that maintain co-factor balance. United States.
Bowie, James U., Opgenorth, Paul H., and Korman, Tyler P.. Tue . "Synthetic biochemistry molecular purge valve module that maintain co-factor balance". United States. https://www.osti.gov/servlets/purl/1502469.
@article{osti_1502469,
title = {Synthetic biochemistry molecular purge valve module that maintain co-factor balance},
author = {Bowie, James U. and Opgenorth, Paul H. and Korman, Tyler P.},
abstractNote = {The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {2}
}

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Works referenced in this record:

Cofactor engineering in Saccharomyces cerevisiae: Expression of a H2O-forming NADH oxidase and impact on redox metabolism
journal, July 2006


A synthetic biochemistry molecular purge valve module that maintains redox balance
journal, June 2014


Escherichia coli Malic Enzymes: Two Isoforms with Substantial Differences in Kinetic Properties, Metabolic Regulation, and Structure
journal, June 2007


Enzyme-catalyzed poly(3-hydroxybutyrate) synthesis from acetate with CoA recycling and NADPH regeneration in Vitro
journal, January 2003