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Title: Modulating laccase enzyme to regulate cell wall biosynthesis and recalcitrance in plants

Abstract

This disclosure provides genetically modified plants having desirable levels of sugar release and syringyl/guaiacyl (S/G) ratio; methods of genetically modifying plants to modulate sugar release and S/G ratio; and uses of such plants. The inventors have determined that genetic modification of a laccase gene (LAC2) from Populus, encoded by locus Potri.008G064000 resulted in transgenic Populus trees with changes in syringyl/guaiacyl ratios as well as altered sugar release phenotypes. Plants with altered sugar release, and S/G ratio, based on modulation of the expression or activity of the LAC2 gene, have divergent uses including pulp and paper production, and biofuel and bioproducts production.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568145
Patent Number(s):
10246719
Application Number:
15/647,819
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 07/12/2017
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Chen, Jin-Gui, Gunter, Lee E., Jawdy, Sara S., Yang, Xiaohan, Tuskan, Gerald A., and Bryan, Anthony Christian. Modulating laccase enzyme to regulate cell wall biosynthesis and recalcitrance in plants. United States: N. p., 2019. Web.
Chen, Jin-Gui, Gunter, Lee E., Jawdy, Sara S., Yang, Xiaohan, Tuskan, Gerald A., & Bryan, Anthony Christian. Modulating laccase enzyme to regulate cell wall biosynthesis and recalcitrance in plants. United States.
Chen, Jin-Gui, Gunter, Lee E., Jawdy, Sara S., Yang, Xiaohan, Tuskan, Gerald A., and Bryan, Anthony Christian. Tue . "Modulating laccase enzyme to regulate cell wall biosynthesis and recalcitrance in plants". United States. https://www.osti.gov/servlets/purl/1568145.
@article{osti_1568145,
title = {Modulating laccase enzyme to regulate cell wall biosynthesis and recalcitrance in plants},
author = {Chen, Jin-Gui and Gunter, Lee E. and Jawdy, Sara S. and Yang, Xiaohan and Tuskan, Gerald A. and Bryan, Anthony Christian},
abstractNote = {This disclosure provides genetically modified plants having desirable levels of sugar release and syringyl/guaiacyl (S/G) ratio; methods of genetically modifying plants to modulate sugar release and S/G ratio; and uses of such plants. The inventors have determined that genetic modification of a laccase gene (LAC2) from Populus, encoded by locus Potri.008G064000 resulted in transgenic Populus trees with changes in syringyl/guaiacyl ratios as well as altered sugar release phenotypes. Plants with altered sugar release, and S/G ratio, based on modulation of the expression or activity of the LAC2 gene, have divergent uses including pulp and paper production, and biofuel and bioproducts production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {4}
}

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