Method and device for ion mobility separations
Abstract
Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a single non-planar surface. Arrays of electrodes are coupled to the surface. A combination of RF and DC voltages are applied to the arrays of electrodes to create confining and driving fields that move ions through the device. The DC voltages are static DC voltages or time-dependent DC potentials or waveforms.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1369062
- Patent Number(s):
- 9704701
- Application Number:
- 14/851,935
- Assignee:
- Battelle Memorial Institute
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- AC0576RLO1830
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Sep 11
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Ibrahim, Yehia M., Garimella, Sandilya V. B., and Smith, Richard D. Method and device for ion mobility separations. United States: N. p., 2017.
Web.
Ibrahim, Yehia M., Garimella, Sandilya V. B., & Smith, Richard D. Method and device for ion mobility separations. United States.
Ibrahim, Yehia M., Garimella, Sandilya V. B., and Smith, Richard D. Tue .
"Method and device for ion mobility separations". United States. https://www.osti.gov/servlets/purl/1369062.
@article{osti_1369062,
title = {Method and device for ion mobility separations},
author = {Ibrahim, Yehia M. and Garimella, Sandilya V. B. and Smith, Richard D.},
abstractNote = {Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a single non-planar surface. Arrays of electrodes are coupled to the surface. A combination of RF and DC voltages are applied to the arrays of electrodes to create confining and driving fields that move ions through the device. The DC voltages are static DC voltages or time-dependent DC potentials or waveforms.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 11 00:00:00 EDT 2017},
month = {Tue Jul 11 00:00:00 EDT 2017}
}
Works referenced in this record:
Ion mobility spectrometer
patent, October 1988
- Eiceman, Gary A.; Leasure, Craig S.
- US Patent Document 4,777,363
Method and device for the reflection of charged particles on surfaces
patent, November 1996
- Franzen, Jochen
- US Patent Document 5,572,035
Ion mobility spectrometer utilizing flexible printed circuit board and method for manufacturing thereof
patent, November 1998
- Yoon, Kyoung Won; Hwang, Ki Woon; Lim, Ho Jin
- US Patent Document 5,834,771
Use of 5HT.sub.1B receptor antagonist for the treatment of vascular disease
patent, August 2000
- Parsons, Andrew
- US Patent Document 6,107,328
Ring pole ion guide apparatus, systems and method
patent, July 2002
- Russ, IV, Charles W.; Fischer, Steven M.
- US Patent Document 6,417,511
Mass spectrometer
patent, November 2005
- Bateman, Robert Harold; Giles, Kevin; Pringle, Steve
- US Patent Document 6,960,760
RF surfaces and RF ion guides
patent, April 2008
- Whitehouse, Craig M.; Welkie, David G.; Cousins, Lisa
- US Patent Document 7,365,317
Ion guides with RF diaphragm stacks
patent, June 2008
- Stoermer, Carsten; Brekenfeld, Andreas; Wehkamp, Thomas
- US Patent Document 7,391,021
RF surfaces and RF ion guides
patent, August 2010
- Whitehouse, Craig M.; Welkie, David G.; Cousins, Lisa
- US Patent Document 7,786,435
Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry
patent, November 2010
- Park, Melvin A.
- US Patent Document 7,838,826
Ion funnel ion trap and process
patent, February 2011
- Belov, Mikhail E.; Ibrahim, Yehia M.; Clowers, Biran H.
- US Patent Document 7,888,635
Microfabricated linear Paul-Straubel ion trap
patent, April 2011
- Mangan, Michael A.; Blain, Matthew G.; Tigges, Chris P.
- US Patent Document 7,928,375
Ion guide device, ion reactor, and mass analyzer
patent, November 2011
- Satake, Hiroyuki; Baba, Takashi; Waki, Izumi
- US Patent Document 8,049,169
Ion guide for mass spectrometers
patent, July 2012
- Kim, Taeman; Parks, Melvin
- US Patent Document 8,222,597
Ion manipulation device
patent, September 2014
- Anderson, Gordon A.; Smith, Richard D.; Ibrahim, Yehia M.
- US Patent Document 8,835,839
Ion mobility spectrometer with high ion transmission efficiency
patent-application, July 2003
- Li, Gangqiang
- US Patent Application 10/053077; 20030132379
Mass spectrometer
patent-application, February 2004
- Bateman, Robert Harold; Giles, Kevin; Pringle, Steve
- US Patent Application 10/448057; 20040026611
Directing and focusing of charged particles with conductive traces on a pliable substrate
patent-application, May 2004
- Foley, Peter
- US Patent Application 10/293237; 20040089803
Automated Analysis Of Complex Matrices Using Mass Spectrometer
patent-application, June 2007
- Keiser, Byron
- US Patent Application 11/567281; 20070138384
Method And Apparatus For Ion Manipulation Using Mesh In A Radio Frequency Field
patent-application, August 2011
- Verentchikov, Anatoli N.
- US Patent Application 13/056167; 20110192969
Ion Mobility Separator with Variable Effective Length
patent-application, January 2015
- Green, Martin Raymond; Langridge, David J.; Wildgoose, Jason Lee
- US Patent Application 14/479805; 20150028200
Development of a new ion mobility time-of-flight mass spectrometer
journal, February 2015
- Ibrahim, Yehia M.; Baker, Erin S.; Danielson, William F.
- International Journal of Mass Spectrometry, Vol. 377
A method for direct measurement of ion mobilities using a travelling wave ion guide
journal, December 2010
- Giles, Kevin; Wildgoose, Jason L.; Langridge, David J.
- International Journal of Mass Spectrometry, Vol. 298, Issue 1-3
An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument
journal, March 2007
- Pringle, Steven D.; Giles, Kevin; Wildgoose, Jason L.
- International Journal of Mass Spectrometry, Vol. 261, Issue 1
Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations
journal, September 2014
- Webb, Ian K.; Garimella, Sandilya V. B.; Tolmachev, Aleksey V.
- Analytical Chemistry, Vol. 86, Issue 19, p. 9632-9637
Fundamentals of Traveling Wave Ion Mobility Spectrometry
journal, December 2008
- Shvartsburg, Alexandre A.; Smith, Richard D.
- Analytical Chemistry, Vol. 80, Issue 24, p. 9689-9699
Applications of a travelling wave-based radio-frequency-only stacked ring ion guide
journal, October 2004
- Giles, Kevin; Pringle, Steven D.; Worthington, Kenneth R.
- Rapid Communications in Mass Spectrometry, Vol. 18, Issue 20, p. 2401-2414
Effects of Select Anions from the Hofmeister Series on the Gas-Phase Conformations of Protein Ions Measured with Traveling-Wave Ion Mobility Spectrometry/Mass Spectrometry
journal, September 2011
- Merenbloom, Samuel I.; Flick, Tawnya G.; Daly, Michael P.
- Journal of The American Society for Mass Spectrometry, Vol. 22, Issue 11, p. 1978-1990
Enhancements in travelling wave ion mobility resolution
journal, May 2011
- Giles, Kevin; Williams, Jonathan P.; Campuzano, Iain
- Rapid Communications in Mass Spectrometry, Vol. 25, Issue 11, p. 1559-1566
Simulation of Electric Potentials and Ion Motion in Planar Electrode Structures for Lossless Ion Manipulations (SLIM)
journal, September 2014
- Garimella, Sandilya V. B.; Ibrahim, Yehia M.; Webb, Ian K.
- Journal of The American Society for Mass Spectrometry, Vol. 25, Issue 11, p. 1890-1896
Characterization of Ion Dynamics in Structures for Lossless Ion Manipulations
journal, September 2014
- Tolmachev, Aleksey V.; Webb, Ian K.; Ibrahim, Yehia M.
- Analytical Chemistry, Vol. 86, Issue 18, p. 9162-9168
Experimental Evaluation and Optimization of Structures for Lossless Ion Manipulations for Ion Mobility Spectrometry with Time-of-Flight Mass Spectrometry
journal, September 2014
- Webb, Ian K.; Garimella, Sandilya V. B.; Tolmachev, Aleksey V.
- Analytical Chemistry, Vol. 86, Issue 18, p. 9169-9176
Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations
journal, May 2015
- Zhang, Xinyu; Garimella, Sandilya V. B.; Prost, Spencer A.
- Analytical Chemistry, Vol. 87, Issue 12, p. 6010-6016
Ion Trapping for Ion Mobility Spectrometry Measurements in a Cyclical Drift Tube
journal, July 2013
- Glaskin, Rebecca S.; Ewing, Michael A.; Clemmer, David E.
- Analytical Chemistry, Vol. 85, Issue 15, p. 7003-7008
A Tandem Mass Spectrometer for Improved Transmission and Analysis of Large Macromolecular Assemblies
journal, March 2002
- Sobott, Frank; Hernández, Helena; McCammon, Margaret G.
- Analytical Chemistry, Vol. 74, Issue 6, p. 1402-1407