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Title: Modified host cells with efflux pumps

Abstract

The present invention provides for a modified host cell comprising a heterologous expression of an efflux pump capable of transporting an organic molecule out of the host cell wherein the organic molecule at a sufficiently high concentration reduces the growth rate of or is lethal to the host cell.

Inventors:
; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1312679
Patent Number(s):
9428726
Application Number:
13/115,925
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2011 May 25
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 09 BIOMASS FUELS

Citation Formats

Dunlop, Mary J., Keasling, Jay D., and Mukhopadhyay, Aindrila. Modified host cells with efflux pumps. United States: N. p., 2016. Web.
Dunlop, Mary J., Keasling, Jay D., & Mukhopadhyay, Aindrila. Modified host cells with efflux pumps. United States.
Dunlop, Mary J., Keasling, Jay D., and Mukhopadhyay, Aindrila. Tue . "Modified host cells with efflux pumps". United States. https://www.osti.gov/servlets/purl/1312679.
@article{osti_1312679,
title = {Modified host cells with efflux pumps},
author = {Dunlop, Mary J. and Keasling, Jay D. and Mukhopadhyay, Aindrila},
abstractNote = {The present invention provides for a modified host cell comprising a heterologous expression of an efflux pump capable of transporting an organic molecule out of the host cell wherein the organic molecule at a sufficiently high concentration reduces the growth rate of or is lethal to the host cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {8}
}

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Works referenced in this record:

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