Host cell modified to produce lactams
Abstract
The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE; National Science Foundation (NSF)
- OSTI Identifier:
- 1824118
- Patent Number(s):
- 11046981
- Application Number:
- 16/212,515
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AC02-05CH11231; EEC 0540879
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 12/06/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Zhang, Jingwei, and Keasling, Jay D. Host cell modified to produce lactams. United States: N. p., 2021.
Web.
Zhang, Jingwei, & Keasling, Jay D. Host cell modified to produce lactams. United States.
Zhang, Jingwei, and Keasling, Jay D. Tue .
"Host cell modified to produce lactams". United States. https://www.osti.gov/servlets/purl/1824118.
@article{osti_1824118,
title = {Host cell modified to produce lactams},
author = {Zhang, Jingwei and Keasling, Jay D.},
abstractNote = {The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {6}
}
Works referenced in this record:
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Platensimycin Biosynthetic Gene Cluster of Streptomyces Platensis
patent-application, March 2009
- Shen, Ben; Smanski, Michael J.
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Genetically Modified Host Cells for Increased P450 Activity Levels and Methods of Use Thereof
patent-application, September 2008
- Chang, Michelle Chia-Yu; Krupa, Rachel A.; Kizer, Jeffrey Lance
- US Patent Application 12/021974; 20080233623
Host cell modified to produce 2-pyrrolidone
patent, March 2019
- Zhang, Jianzhong; Keasling, Jay D.
- US Patent Document 10,227,622