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Title: Host cell modified to produce lactams

Abstract

The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE; National Science Foundation (NSF)
OSTI Identifier:
1824118
Patent Number(s):
11046981
Application Number:
16/212,515
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
AC02-05CH11231; EEC 0540879
Resource Type:
Patent
Resource Relation:
Patent File Date: 12/06/2018
Country of Publication:
United States
Language:
English

Citation Formats

Zhang, Jingwei, and Keasling, Jay D. Host cell modified to produce lactams. United States: N. p., 2021. Web.
Zhang, Jingwei, & Keasling, Jay D. Host cell modified to produce lactams. United States.
Zhang, Jingwei, and Keasling, Jay D. Tue . "Host cell modified to produce lactams". United States. https://www.osti.gov/servlets/purl/1824118.
@article{osti_1824118,
title = {Host cell modified to produce lactams},
author = {Zhang, Jingwei and Keasling, Jay D.},
abstractNote = {The present invention provides for a genetically modified host cell capable of producing a lactam comprising a 2-pyrrolidone synthase, or an enzymatically active fragment thereof, heterologous to the host cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 29 00:00:00 EDT 2021},
month = {Tue Jun 29 00:00:00 EDT 2021}
}

Works referenced in this record:

Nitric oxide synthase inhibitor phosphate salt
patent-application, May 2014


Platensimycin Biosynthetic Gene Cluster of Streptomyces Platensis
patent-application, March 2009


Genetically Modified Host Cells for Increased P450 Activity Levels and Methods of Use Thereof
patent-application, September 2008


Host cell modified to produce 2-pyrrolidone
patent, March 2019