Solid-state detector and optical system for microchip analyzers
Abstract
A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175277
- Patent Number(s):
- 6867420
- Application Number:
- 10/269,138
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG03-91ER61125
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., and Street, Robert A. Solid-state detector and optical system for microchip analyzers. United States: N. p., 2005.
Web.
Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., & Street, Robert A. Solid-state detector and optical system for microchip analyzers. United States.
Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., and Street, Robert A. Tue .
"Solid-state detector and optical system for microchip analyzers". United States. https://www.osti.gov/servlets/purl/1175277.
@article{osti_1175277,
title = {Solid-state detector and optical system for microchip analyzers},
author = {Mathies, Richard A. and Kamei, Toshihiro and Scherer, James R. and Street, Robert A.},
abstractNote = {A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {3}
}
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