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Title: Solid-state detector and optical system for microchip analyzers

Abstract

A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175277
Patent Number(s):
6867420
Application Number:
10/269,138
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
FG03-91ER61125
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., and Street, Robert A. Solid-state detector and optical system for microchip analyzers. United States: N. p., 2005. Web.
Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., & Street, Robert A. Solid-state detector and optical system for microchip analyzers. United States.
Mathies, Richard A., Kamei, Toshihiro, Scherer, James R., and Street, Robert A. Tue . "Solid-state detector and optical system for microchip analyzers". United States. https://www.osti.gov/servlets/purl/1175277.
@article{osti_1175277,
title = {Solid-state detector and optical system for microchip analyzers},
author = {Mathies, Richard A. and Kamei, Toshihiro and Scherer, James R. and Street, Robert A.},
abstractNote = {A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {3}
}

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