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Title: Hydroxypyridonate and hydroxypyrimidinone chelating agents

Abstract

The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175217
Patent Number(s):
6846915
Application Number:
10/194,502
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., and Thompson, Marlon. Hydroxypyridonate and hydroxypyrimidinone chelating agents. United States: N. p., 2005. Web.
Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., & Thompson, Marlon. Hydroxypyridonate and hydroxypyrimidinone chelating agents. United States.
Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., and Thompson, Marlon. Tue . "Hydroxypyridonate and hydroxypyrimidinone chelating agents". United States. https://www.osti.gov/servlets/purl/1175217.
@article{osti_1175217,
title = {Hydroxypyridonate and hydroxypyrimidinone chelating agents},
author = {Raymond, Kenneth N. and Doble, Daniel M. and Sunderland, Christopher J. and Thompson, Marlon},
abstractNote = {The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {1}
}

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Works referenced in this record:

Force Field Parametrization for Gadolinium Complexes Based on ab Initio Potential Energy Surface Calculations
journal, April 2000


Syntheses and Relaxation Properties of Mixed Gadolinium Hydroxypyridinonate MRI Contrast Agents
journal, December 2000