Hydroxypyridonate and hydroxypyrimidinone chelating agents
Abstract
The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175217
- Patent Number(s):
- 6846915
- Application Number:
- 10/194,502
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., and Thompson, Marlon. Hydroxypyridonate and hydroxypyrimidinone chelating agents. United States: N. p., 2005.
Web.
Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., & Thompson, Marlon. Hydroxypyridonate and hydroxypyrimidinone chelating agents. United States.
Raymond, Kenneth N., Doble, Daniel M., Sunderland, Christopher J., and Thompson, Marlon. Tue .
"Hydroxypyridonate and hydroxypyrimidinone chelating agents". United States. https://www.osti.gov/servlets/purl/1175217.
@article{osti_1175217,
title = {Hydroxypyridonate and hydroxypyrimidinone chelating agents},
author = {Raymond, Kenneth N. and Doble, Daniel M. and Sunderland, Christopher J. and Thompson, Marlon},
abstractNote = {The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {1}
}
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Works referenced in this record:
Force Field Parametrization for Gadolinium Complexes Based on ab Initio Potential Energy Surface Calculations
journal, April 2000
- Villa, Alessandra; Cosentino, Ugo; Pitea, Demetrio
- The Journal of Physical Chemistry A, Vol. 104, Issue 15, p. 3421-3429
Syntheses and Relaxation Properties of Mixed Gadolinium Hydroxypyridinonate MRI Contrast Agents
journal, December 2000
- Cohen, Seth M.; Xu, Jide; Radkov, Emil
- Inorganic Chemistry, Vol. 39, Issue 25, p. 5747-5756