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Title: Detection of electrophilic and nucleophilic chemical agents

Abstract

A "real time" method for detecting chemical agents generally and particularly electrophilic and nucleophilic species by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species. By bonding or otherwise attaching these precursor molecules to a surface or substrate they can be used in numerous applications.

Inventors:
;
Issue Date:
Research Org.:
SNL-A (Sandia National Laboratories, Albuquerque, NM (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1150085
Patent Number(s):
8,802,444
Application Number:
13/553,959
Assignee:
Sandia Corporation (Albuquerque, NM)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

Citation Formats

McElhanon, James R., and Shepodd, Timothy J. Detection of electrophilic and nucleophilic chemical agents. United States: N. p., 2014. Web.
McElhanon, James R., & Shepodd, Timothy J. Detection of electrophilic and nucleophilic chemical agents. United States.
McElhanon, James R., and Shepodd, Timothy J. Tue . "Detection of electrophilic and nucleophilic chemical agents". United States. https://www.osti.gov/servlets/purl/1150085.
@article{osti_1150085,
title = {Detection of electrophilic and nucleophilic chemical agents},
author = {McElhanon, James R. and Shepodd, Timothy J.},
abstractNote = {A "real time" method for detecting chemical agents generally and particularly electrophilic and nucleophilic species by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species. By bonding or otherwise attaching these precursor molecules to a surface or substrate they can be used in numerous applications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {8}
}

Patent:

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