Title: Chemically modified carbonic anhydrases useful in carbon capture systems

Abstract

The present disclosure relates to chemically modified carbonic anhydrase polypeptides and soluble compositions, homogenous liquid formulations comprising them. The chemically modified carbonic anhydrase polypeptides have improved properties relative to the same carbonic anhydrase polypeptide that is not chemically modified including the improved properties of increased activity and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides methods of preparing the chemically modified polypeptides and methods of using the chemically modified polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering.

Inventors:

Novick, Scott J; Alvizo, Oscar

Issue Date:

2013-10-29

Research Org.:

Codexis, Inc. (Redwood City, CA)

Sponsoring Org.:

USDOE

OSTI Identifier:

1107639

Patent Number(s):

8569031

Application Number:

13/721,648

Assignee:

Codexis, Inc. (Redwood City, CA)

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION

B01D53/84 - Biological processes
B01D2252/602 - Activators, promoting agents, catalytic agents or enzymes
B01D2258/0283 - Flue gases
B01D2255/804 - Enzymatic

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N9/88 - Lyases

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION

B01D2252/20489 - with two or more hydroxyl groups
B01D53/1475 - {Removing carbon dioxide}
B01D2257/504 - Carbon dioxide
B01D53/1493 - {Selection of liquid materials for use as absorbents}

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N9/96 - Stabilising an enzyme by forming an adduct or a composition

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION

B01D2252/20484 - with one hydroxyl group

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02P - CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS

Y02P20/59 - Biological synthesis

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DOE Contract Number:  

AR0000071

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY