Human Islet Research Network (HIRN): Alternative Splicing Events

Webb-Robertson, Bobbie-Jo M; Bramer, Lisa M; Flores, Javier; Wu, Wenting; Mirmira, Raghavendra G

doi:10.25584/2331203

Title: Human Islet Research Network (HIRN): Alternative Splicing Events

Dataset
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Abstract

Inclusion levels of alternative splicing (AS) events of five different varieties (i.e. skipped exon (SE), retained intron (RI), alternative 5’ splice site (A5SS), alternative 3’ splice site (A3SS), and mutually exclusive exons (MXE)) were measured in human blood samples from two separate cohorts of patients. Cohort 1 (Training Cohort): 12 healthy controls; 12 new onset type 1 diabetic (T1D) cases cases and controls matched on biological sex, age, and body mass index (BMI) 180 million reads Cohort 2 (Testing Cohort): 12 healthy controls; 12 new onset type 1 diabetic (T1D) cases cases and controls matched on biological sex and age. BMI not recorded. 150 million reads

Authors:

Webb-Robertson, Bobbie-Jo M; Bramer, Lisa M; Flores, Javier; Wu, Wenting; Mirmira, Raghavendra G

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); PNNL
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Publication Date:: Sat May 06 04:00:00 UTC 2023

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE Office of Science (SC)

OSTI Identifier:: 2331203

DOI:: https://doi.org/10.25584/2331203

Citation Formats


                    Webb-Robertson, Bobbie-Jo M, Bramer, Lisa M, Flores, Javier, Wu, Wenting, and Mirmira, Raghavendra G. Human Islet Research Network (HIRN): Alternative Splicing Events.  United States: N. p., 2023. 
        Web.  doi:10.25584/2331203.

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                    Webb-Robertson, Bobbie-Jo M, Bramer, Lisa M, Flores, Javier, Wu, Wenting, & Mirmira, Raghavendra G. Human Islet Research Network (HIRN): Alternative Splicing Events.  United States.  doi:https://doi.org/10.25584/2331203

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                    Webb-Robertson, Bobbie-Jo M, Bramer, Lisa M, Flores, Javier, Wu, Wenting, and Mirmira, Raghavendra G. 2023.  
"Human Islet Research Network (HIRN): Alternative Splicing Events".  United States.  doi:https://doi.org/10.25584/2331203.  https://www.osti.gov/servlets/purl/2331203. Pub date:Sat May 06 04:00:00 UTC 2023

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@article{osti_2331203,

  title        = {Human Islet Research Network (HIRN): Alternative Splicing Events},

  author       = {Webb-Robertson, Bobbie-Jo M and Bramer, Lisa M and Flores, Javier and Wu, Wenting and Mirmira, Raghavendra G},

  abstractNote = {Inclusion levels of alternative splicing (AS) events of five different varieties (i.e. skipped exon (SE), retained intron (RI), alternative 5’ splice site (A5SS), alternative 3’ splice site (A3SS), and mutually exclusive exons (MXE)) were measured in human blood samples from two separate cohorts of patients. Cohort 1 (Training Cohort): 12 healthy controls; 12 new onset type 1 diabetic (T1D) cases cases and controls matched on biological sex, age, and body mass index (BMI) 180 million reads Cohort 2 (Testing Cohort): 12 healthy controls; 12 new onset type 1 diabetic (T1D) cases cases and controls matched on biological sex and age. BMI not recorded. 150 million reads},

  doi          = {10.25584/2331203},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {Sat May 06 04:00:00 UTC 2023},

  month        = {Sat May 06 04:00:00 UTC 2023}

}

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DOI: https://doi.org/10.25584/2331203

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