Structural basis for receptor selectivity and inverse agonism in S1P5 receptors

Lyapina, Elizaveta

doi:10.11577/1881337

Title: Structural basis for receptor selectivity and inverse agonism in S1P5 receptors

Abstract

This dataset contains a subset of raw diffraction images for the serial femtosecond crystallography data of S1P5-ONO-5430608 complex. The diffraction data contain a strong systematic background as described in Lyapina et al. No additional background subtraction was applied to the data. In order to avoid its effects, the background subtraction implemented in CrystFEL, was applied (--rings-grad subtraction). The final stream, supplemented with this dataset, was obtained with: indexamajig 0.8.0 Respectively, the hkl file was obtained with: partialator 0.8.0

Authors:: Lyapina, Elizaveta

Publication Date:: 2022-08-15

Other Number(s):: CXIDB ID 196

DOE Contract Number:: AC02-05CH11231

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Coherent X-ray Imaging Data Bank; USC

Sponsoring Org.:: USC

Keywords:: XFEL; X-ray Free-electorn Lasers; Serial Femtosecond Crystallography; NCI; Human sphingosine-1-phosphate receptor 5 (S1P5) in complex with ONO-5430608 inverse agonist; PAL-XFEL

OSTI Identifier:: 1881337

DOI:: https://doi.org/10.11577/1881337

Citation Formats


                    Lyapina, Elizaveta. Structural basis for receptor selectivity and inverse agonism in S1P5 receptors.  United States: N. p., 2022. 
        Web.  doi:10.11577/1881337.

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                    Lyapina, Elizaveta. Structural basis for receptor selectivity and inverse agonism in S1P5 receptors.  United States.  doi:https://doi.org/10.11577/1881337

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                    Lyapina, Elizaveta. 2022.  
"Structural basis for receptor selectivity and inverse agonism in S1P5 receptors".  United States.  doi:https://doi.org/10.11577/1881337.  https://www.osti.gov/servlets/purl/1881337. Pub date:Mon Aug 15 00:00:00 EDT 2022

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@article{osti_1881337,

  title        = {Structural basis for receptor selectivity and inverse agonism in S1P5 receptors},

  author       = {Lyapina, Elizaveta},

  abstractNote = {This dataset contains a subset of raw diffraction images for the serial femtosecond crystallography data of S1P5-ONO-5430608 complex. The diffraction data contain a strong systematic background as described in Lyapina et al. No additional background subtraction was applied to the data. In order to avoid its effects, the background subtraction implemented in CrystFEL, was applied (--rings-grad subtraction). The final stream, supplemented with this dataset, was obtained with: indexamajig 0.8.0 Respectively, the hkl file was obtained with: partialator 0.8.0},

  doi          = {10.11577/1881337},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {2022},

  month        = {8}

}

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DOI: https://doi.org/10.11577/1881337

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