Detection of polyaromatic compounds using antibody-based fiberoptics fluoroimmunosensors
Conference
·
OSTI ID:5069306
In this work we have investigated the performance of an antibody-based fiberoptics sensor for the detection of the carcinogen benzo(a)pyrene and its DNA-adduct product BP-tetrol. The excellent sensitivity of this device - femtomole limits of detection for BP - illustrates that it has considerable potential to perform analyses of chemical and biological samples at trace levels in complex matrices. The results indicate that fiberoptics-based fluoroimmunosensors can be useful in a wide spectrum of biochemical and clinical analyses. 17 refs., 4 figs., 1 tab.
- Research Organization:
- Oak Ridge National Lab., TN (USA); Tennessee Univ., Knoxville (USA). Dept. of Chemistry
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 5069306
- Report Number(s):
- CONF-870940-5; ON: DE88009065
- Resource Relation:
- Conference: 11. international symposium on polynuclear aromatic hydrocarbons, Gaithersburg, MD, USA, 23 Sep 1987
- Country of Publication:
- United States
- Language:
- English
Similar Records
Immunofluorescence detection for fiberoptics chemical and biological sensors
Antibody-based fiberoptics biosensor for the carcinogen benzo(a)pyrene
Fiberoptics immunofluorescence spectroscopy for chemical and biological monitoring
Conference
·
Fri Jan 01 00:00:00 EST 1988
·
OSTI ID:5069306
+3 more
Antibody-based fiberoptics biosensor for the carcinogen benzo(a)pyrene
Journal Article
·
Wed Jul 01 00:00:00 EDT 1987
· Appl. Spectrosc.; (United States)
·
OSTI ID:5069306
+3 more
Fiberoptics immunofluorescence spectroscopy for chemical and biological monitoring
Conference
·
Tue Jan 01 00:00:00 EST 1985
·
OSTI ID:5069306
+2 more
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
BENZOPYRENE
IMMUNOASSAY
DNA ADDUCTS
FIBER OPTICS
FLUORESCENCE SPECTROSCOPY
ADDUCTS
AROMATICS
CONDENSED AROMATICS
EMISSION SPECTROSCOPY
HYDROCARBONS
ORGANIC COMPOUNDS
SPECTROSCOPY
560300* - Chemicals Metabolism & Toxicology
400102 - Chemical & Spectral Procedures
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
BENZOPYRENE
IMMUNOASSAY
DNA ADDUCTS
FIBER OPTICS
FLUORESCENCE SPECTROSCOPY
ADDUCTS
AROMATICS
CONDENSED AROMATICS
EMISSION SPECTROSCOPY
HYDROCARBONS
ORGANIC COMPOUNDS
SPECTROSCOPY
560300* - Chemicals Metabolism & Toxicology
400102 - Chemical & Spectral Procedures