Phthalamide-lanthanide complexes for use as luminescent markers

Raymond, Kenneth N; Petoud, Stephane; Cohen, Seth; Xu, Jide

Phthalamide-lanthanide complexes for use as luminescent markers

Patent · Tue Oct 28 00:00:00 EDT 2008

OSTI ID:985174

Raymond, Kenneth N ^[1]; Petoud, Stephane ^[2]; Cohen, Seth ^[3]; Xu, Jide ^[1]

Berkeley, CA
Pittsburgh, PA
Boston, MA

The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one phthalamidyl moiety. Also provided are probes incorporating the phthalamidyl ligands of the invention and methods utilizing the ligands of the invention and probes comprising the ligands of the invention.

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Research Organization:: University of California

Sponsoring Organization:: USDOE

DOE Contract Number:: AC03-76SF00098

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 7,442,558

Application Number:: 10/867,882

OSTI ID:: 985174

Country of Publication:: United States

Language:: English

References (15)

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Development of luminescent lanthanide chelate labels for diagnostic assays Hemmilä, Ilkka; Mukkala, Veli-Matti; Takalo, Harri Journal of Alloys and Compounds, Vol. 249, Issue 1-2, p. 158-162 https://doi.org/10.1016/S0925-8388(96)02834-4	journal	March 1997
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Mono(di)nuclear Europium(III) Complexes of Macrobi(tri)cyclic Cryptands Derived from Diazatetralactams as Luminophores in Aqueous Solution Galaup, Chantal; Picard, Claude; Cathala, Bernard Helvetica Chimica Acta, Vol. 82, Issue 4, p. 543-560 https://doi.org/10.1002/(SICI)1522-2675(19990407)82:4<543::AID-HLCA543>3.0.CO;2-U	journal	April 1999
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