Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Acoustic monitoring method and system in laser-induced optical breakdown (LIOB)

Patent ·
OSTI ID:984344

An acoustic monitoring method and system in laser-induced optical breakdown (LIOB) provides information which characterize material which is broken down, microbubbles in the material, and/or the microenvironment of the microbubbles. In one embodiment of the invention, femtosecond laser pulses are focused just inside the surface of a volume of aqueous solution which may include dendrimer nanocomposite (DNC) particles. A tightly focused, high frequency, single-element ultrasonic transducer is positioned such that its focus coincides axially and laterally with this laser focus. When optical breakdown occurs, a microbubble forms and a shock or pressure wave is emitted (i.e., acoustic emission). In addition to this acoustic signal, the microbubble may be actively probed with pulse-echo measurements from the same transducer. After the microbubble forms, received pulse-echo signals have an extra pulse, describing the microbubble location and providing a measure of axial microbubble size. Wavefield plots of successive recordings illustrate the generation, growth, and collapse of microbubbles due to optical breakdown. These same plots can also be used to quantify LIOB thresholds.

Research Organization:
University of Michigan
Sponsoring Organization:
USDOE
DOE Contract Number:
FG01-00NE22943
Assignee:
The Regents of the University of Michigan (Ann Arbor, MI)
Patent Number(s):
7,367,948
Application Number:
10/643,659
OSTI ID:
984344
Country of Publication:
United States
Language:
English

References (8)

Role of Laser-Induced Plasma Formation in Pulsed Cellular Microsurgery and Micromanipulation journal February 2002
Behavior of laser-induced cavitation bubbles in liquid nitrogen journal November 2000
Acoustic characterization of microbubble dynamics in laser-induced optical breakdown journal May 2003
Acoustic detection of laser induced optical breakdown in dendrimer nanocomposites: implications for site targeted molecular diagnostics and therapeutics conference January 2002
Optical and Acoustical Dynamics of Microbubble Contrast Agents inside Neutrophils journal March 2001
Enhancement of laser-induced optical breakdown using metal/dendrimer nanocomposites journal March 2002
Influence of pulse duration on mechanical effects after laser-induced breakdown in water journal June 1998
Acoustic detection of microbubble formation induced by enhanced optical breakdown of silver/dendrimer nanocomposites journal February 2003

Similar Records

Acoustic emission and magnification of atomic lines resolution for laser breakdown of salt water in ultrasound field
Journal Article · Wed Oct 28 00:00:00 EDT 2015 · AIP Conference Proceedings · OSTI ID:22492623

Application of electromagnetic acoustic transducers to coarse-grained material
Technical Report · Mon Jul 01 00:00:00 EDT 1991 · OSTI ID:5640464

Opto-acoustic transducer for medical applications
Patent · Tue Aug 31 00:00:00 EDT 1999 · OSTI ID:678576

Related Subjects