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A graphene-based electrochemical sensor for sensitive detection of paracetamol

Journal Article · · Talanta, 81(3):754-759

An electrochemical sensor based on the electrocatalytic activity of functionalized graphene for sensitive detection of paracetamol is presented. The electrochemical behaviors of paracetamol on graphene-modified glassy carbon electrodes (GCEs) were investigated by cyclic voltammetry and square-wave voltammetry. The results showed that the graphene-modified electrode exhibited excellent electrocatalytic activity to paracetamol. A quasi-reversible redox process of paracetamol at the modified electrode was obtained, and the over-potential of paracetamol decreased significantly compared with that at the bare GCE. Such electrocatalytic behavior of graphene is attributed to its unique physical and chemical properties, e.g., subtle electronic characteristics, attractive π–π interaction, and strong adsorptive capability. The sensor shows great promise for simple, sensitive, and quantitative detection of paracetamol.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
OSTI ID:
982000
Report Number(s):
PNNL-SA-71976; 30493
Journal Information:
Talanta, 81(3):754-759, Journal Name: Talanta, 81(3):754-759 Journal Issue: 3 Vol. 81; ISSN 0039-9140
Country of Publication:
United States
Language:
English