Dynamical Transition in Hydrated Biomolecules, Native and Denatured
Journal Article
·
· Journal of Biological Physics
- ORNL
We use elastic neutron scattering to demonstrate that a sharp increase in the mean-squared atomic displacements, commonly observed in hydrated proteins above 200 K and often referred to as the dynamical transition, is present in the hydrated state of both native and denatured lysozyme. A direct comparison of the native and denatured protein thus confirms that the presence of the transition in the mean-squared atomic displacements is not specific to biologically functional molecules.
- Research Organization:
- Oak Ridge National Laboratory (ORNL); Spallation Neutron Source
- Sponsoring Organization:
- SC USDOE - Office of Science (SC)
- DOE Contract Number:
- AC05-00OR22725
- OSTI ID:
- 979216
- Journal Information:
- Journal of Biological Physics, Journal Name: Journal of Biological Physics Journal Issue: 3 Vol. 36
- Country of Publication:
- United States
- Language:
- English
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