Vinyl Dimethyl Azlactone-Containing Copolymers: Towards Bio-Inspired Surfaces/Polymer-Protein Conjugates
- ORNL
- Clemson University
Stimuli-responsive, vinyl dimethyl azlactone/vinyl pyrrolidone (VDMA/VP) copolymers have been prepared using free radical polymerization techniques. These copolymers are subsequently the basis for the design of polymer brushes where the system is composed of a polystyrene (PS) block and a VDMA/VP copolymer block. Copolymers have been prepared using reversible addition fragmentation chain transfer (RAFT) polymerization technique. Using a solvent that is selective for the VDMA/VP block, these PS-block-P[VDMA/VP] copolymers can be preferentially adsorbed at the solid-fluid interface through the PS block to form a polymer "brush". Because VDMA is known to quantitatively react with amines, exposure of the copolymer to a solution containing amino acids (e.g. glycine) yields a bio-functionalized polymer brush. In this paper we will report on the synthesis and characterization of VDMA/VP copolymers including compositional analysis using FTIR and NMR spectroscopies.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Sciences (CNMS)
- Sponsoring Organization:
- USDOE Office of Science (SC)
- DOE Contract Number:
- DE-AC05-00OR22725
- OSTI ID:
- 978777
- Resource Relation:
- Conference: The Waterborne Symposium Advances in Intelligent Coatings Design, New Orleans, USA, 20070214, 20070216
- Country of Publication:
- United States
- Language:
- English
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