Extracytoplasmic PAS-like domains are common in signal transduction proteins.
We present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain.
- Research Organization:
- Argonne National Laboratory (ANL)
- Sponsoring Organization:
- SC; NIH
- DOE Contract Number:
- AC02-06CH11357
- OSTI ID:
- 977044
- Report Number(s):
- ANL/BIO/JA-65883
- Journal Information:
- J. Bacteriol., Journal Name: J. Bacteriol. Journal Issue: 4 ; Feb. 2010 Vol. 192; ISSN JOBAAY; ISSN 0021-9193
- Country of Publication:
- United States
- Language:
- ENGLISH
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