Assessment of the Technologies for Molecular Biodosimetry for Human Low-Dose Radiation Exposure Symposium: Agenda and Abstracts

Conference · Mon Nov 16 00:00:00 EST 2009

OSTI ID:967317

Coleman, Matthew A. ^[1]; Ramakrishnan, Narayani ^[2]

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1. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2. National Inst. of Allergy and Infectious Diseases, Bethesda, MD (United States)

In the event of a radiological accident, the rapid evaluation of the individual absorbed dose is paramount to discriminate those individuals who must receive medical attention. New research with genomic- and proteomic-wide tools is showing that within minutes to hours after exposure to ionizing radiation the cellular machinery is modified. For example: large-scale changes occur in the gene expression profiles involving a broad variety of cellular pathways after a wide range of both low dose (<10 cGy) and high dose (>10 cGy) ionizing radiation exposures. Symposium 12 was organized to address a wide range of biological effects using the latest technologies. To address current models following ionizing radiation exposure, methods in biodosimetry and dose effects the symposia featured a general overview titled “Model Systems and Current Approaches in Biodosimetry” by Matthew A. Coleman, from Lawrence Livermore National Laboratory and a talk entitled “Brief Overview of Biodosimetry Projects in the NIH Rad/Nuc Program” by Dr. Narayani Ramakrishnan, National Institute of Allergy and Infectious Diseases. These two talk set the tone for issues in data and model integration as well as addressing the national need for robust technologies for biological dosimetry. The report continues with more description of the presentations, along with the agenda and abstracts of the papers presented.

• Research Organization: Environmental Mutagen Society, Reston, VA (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: FG02-07ER64474
• OSTI ID: 967317
• Report Number(s): DOE/ER-64474; Final Report 2007 EMS AM; TRN: US201002%%877
• Resource Relation: Conference: 38. Assessment of the Technologies for Molecular Biodosimetry for Human Low-Dose Radiation Exposure Symposium, Atlanta, GA (United States), 22 Oct 2007
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOCHEMISTRY
BIOLOGICAL EFFECTS
CHROMOSOMAL ABERRATIONS
DNA DAMAGES
DOSIMETRY
EVALUATION
GENES
GENETICS
HEMATOLOGY
IMMUNOLOGY
IN VIVO
IONIZING RADIATIONS
LYMPHOCYTES
PROCESSING
PROTEINS
RADIATION ACCIDENTS
RADIATION DOSES
RADIATIONS