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Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis

Patent ·
OSTI ID:961572
 [1];  [2];  [3];  [4];  [4];  [4];  [4]
  1. Tracy, CA
  2. San Mateo, CA
  3. Berkeley, CA
  4. Livermore, CA
+ Show Author Affiliations

Described herein is the identification of nucleotide sequences specific to Francisella tularensis that serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
W-7405-ENG-48
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Number(s):
7,494,778
Application Number:
11/644,669
OSTI ID:
961572
Country of Publication:
United States
Language:
English

References (3)

Detection of Francisella tularensis in blood by polymerase chain reaction. journal January 1993
Sequencing of the Francisella tularensis Strain Schu 4 Genome Reveals the Shikimate and Purine Metabolic Pathways, Targets for the Construction of a Rationally Attenuated Auxotrophic Vaccine journal March 2000
Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4 journal October 2001

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