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Title: Precise and automated microfluidic sample preparation.

Conference ·
OSTI ID:959089

Autonomous bio-chemical agent detectors require sample preparation involving multiplex fluid control. We have developed a portable microfluidic pump array for metering sub-microliter volumes at flowrates of 1-100 {micro}L/min. Each pump is composed of an electrokinetic (EK) pump and high-voltage power supply with 15-Hz feedback from flow sensors. The combination of high pump fluid impedance and active control results in precise fluid metering with nanoliter accuracy. Automated sample preparation will be demonstrated by labeling proteins with fluorescamine and subsequent injection to a capillary gel electrophoresis (CGE) chip.

Research Organization:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
OSTI ID:
959089
Report Number(s):
SAND2004-3708C; TRN: US201001%%151
Resource Relation:
Conference: Proposed for presentation at the MicroTAS 2004 held September 26-30, 3004 in Malmo, Sweden.
Country of Publication:
United States
Language:
English