A Novel Class of Metal-Directed Supramolecular DNA-Delivery Systems
Journal Article
·
· Chem.Commun.2007:2944,2007
OSTI ID:953927
The bis-complexes [Cu(L{sub dt}){sub 2}](OTf){sub 2} ( 1) and [Cu(L{sub ot}){sub 2}](OTf){sub 2} ( 2), where L{sub dt} = 1-dodecyl-1,4,7-triazacyclononane, L{sup ot} = 1-octadecyl-1,4,7-triazacyclononane and OTf = trifluoromethanesulfonate, formed a novel class of metallo-liposomes in water that transfect pEGFP-N1 plasmids into HEK 293-T cells at 38% and 4% efficiency, respectively.
- Research Organization:
- SLAC National Accelerator Lab., Menlo Park, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC02-76SF00515
- OSTI ID:
- 953927
- Report Number(s):
- SLAC-REPRINT-2009-465; TRN: US201004%%664
- Journal Information:
- Chem.Commun.2007:2944,2007, Vol. 2007; ISSN 1359-7345
- Country of Publication:
- United States
- Language:
- English
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