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Automated Eukaryotic Gene Structure Annotation Using EVidenceModeler and the Program to Assemble Spliced Alignments

Journal Article · · Genome Biology, n/a, no. 9, January 11, 2008, r7
OSTI ID:941402
EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program to Assemble Spliced Alignments (PASA), yields a comprehensive, configurable annotation system that predicts protein-coding genes and alternatively spliced isoforms. Our experiments on both rice and human genome sequences demonstrate that EVM produces automated gene structure annotation approaching the quality of manual curation.
Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA
Sponsoring Organization:
USDOE
DOE Contract Number:
W-7405-ENG-48
OSTI ID:
941402
Report Number(s):
UCRL-JRNL-237232
Journal Information:
Genome Biology, n/a, no. 9, January 11, 2008, r7, Journal Name: Genome Biology, n/a, no. 9, January 11, 2008, r7 Journal Issue: 1 Vol. 9
Country of Publication:
United States
Language:
English

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