Methidium intercalator inserted into synthetic oligonucleotides.
Journal Article
·
· Tetrahedron Lett.
A new methidium intercalator phosphoramidite has been synthesized. Methidium incorporation into an oligonucleotide during the synthesis was confirmed by UV and MALDI TOF MS data. UV melting experiments showed enhanced stability of a duplex, containing internal methidium. Methidium phosphoramidite has been synthesized and used for insertion of intercalator into the deoxyoligonucleotides.
- Research Organization:
- Argonne National Laboratory (ANL)
- DOE Contract Number:
- AC02-06CH11357
- OSTI ID:
- 937899
- Report Number(s):
- ANL/CMB/JA-23413
- Journal Information:
- Tetrahedron Lett., Journal Name: Tetrahedron Lett. Journal Issue: 47 ; 1996 Vol. 37; ISSN TELEAY; ISSN 0040-4039
- Country of Publication:
- United States
- Language:
- ENGLISH
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