Nanomaterial Labels in Electrochemical Immunosensors and Immunoassays
This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterial–antibody-antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 921390
- Report Number(s):
- PNNL-SA-57585; 24822; 400412000
- Journal Information:
- Talanta, 74(3):308-317, Journal Name: Talanta, 74(3):308-317 Journal Issue: 3 Vol. 74; ISSN 0039-9140; ISSN TLNTA2
- Country of Publication:
- United States
- Language:
- English
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