Longitudinal Bank for Serum, Plasma, and DNA for Detection of Biomarkers

Technical Report · Mon Nov 12 04:00:00 EST 2007

DOI:https://doi.org/10.2172/919465· OSTI ID:919465

Vogelzang, Nicolas ^[1]; Fink, Louis ^[2]

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1. Nevada Cancer Inst., Las Vegas, NV (United States); Nevada Cancer Institute
2. Nevada Cancer Inst., Las Vegas, NV (United States)

The discovery of genetic or biochemical markers to discriminate malignant cancers from normal or benign disease states, markers to stage cancer or monitor disease progression and markers that provide an early indication of an individual’s response to chemotherapy have become a major research objectives of the oncology community over the past few years. The goal of the project is to create a patient specimen bank of serum, plasma, urine and tissues from approximately 1500 individuals. The collection of samples from individuals on a longitudinal basis provided proteomic and biochemical data to be correlated with clinical endpoints. This greatly enhanced our ability to identify biomarkers for staging different cancers and to detect patient responsiveness to therapy at an early state in the treatment process.

• Research Organization: Nevada Cancer Inst., Las Vegas, NV (United States)
• Sponsoring Organization: USDOE
• Contributing Organization: ACQ
• DOE Contract Number: FG02-06ER64280
• OSTI ID: 919465
• Report Number(s): AnnualER--64280
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES