Phylo-VISTA: An interactive visualization tool for multiple DNAsequence alignments
Motivation. The power of multi-sequence comparison forbiological discovery is well established and sequence data from a growinglist of organisms is becoming available. Thus, a need exists forcomputational strategies to visually compare multiple aligned sequencesto support conservation analysis across various species. To be efficientthese visualization algorithms require the ability to universally handlea wide range of evolutionary distances while taking into accountphylogeny Results. We have developed Phylo-VISTA, an interactive tool foranalyzing multiple alignments by visualizing the similarity of DNAsequences among multiple species while considering their phylogenicrelationships. Features include a broad spectrum of resolution parametersfor examining the alignment and the ability to easily compare any subtreeof sequences within a complete alignment dataset. Phylo-VISTA uses VISTAconcepts that have been successfully applied previously to a wide rangeof comparative genomics data analysis problems. Availability Phylo-VISTAis an interactive java applet available for downloading athttp://graphics.cs.ucdavis.edu/~;nyshah/Phylo-VISTA. It is also availableon-line at http://www-gsd.lbl.gov/phylovista and is integrated with theglobal alignment program LAGAN athttp://lagan.stanford.edu.Contactphylovista@lbl.gov
- Research Organization:
- COLLABORATION - UCDavis
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- DE-AC02-05CH11231
- OSTI ID:
- 918099
- Report Number(s):
- LBNL-52539; R&D Project: 863R1A; BnR: 400412000; TRN: US200817%%1117
- Journal Information:
- Bioinformatics, Vol. 20, Issue 5; Related Information: Journal Publication Date: 03/22/2004
- Country of Publication:
- United States
- Language:
- English
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Phylo-vista: Interactive visualization of multiple DNA sequence alignments
Phylo-VISTA: An Interactive Visualization Tool for Multiple DNA Sequence Alignments