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De novo interstitial deletion q16.2q21 on chromosome 6

Journal Article · · American Journal of Medical Genetics
; ;  [1]
  1. Universidad Complutense, Madrid (Spain); and others

A de novo interstitial deletion of 6q16.2q21 was observed in a 23-month-old boy with mental and psychomotor delay, obese appearance, minor craniofacial anomalies, and brain anomalies. We compare clinical manifestations of this patient with those observed in previously reported cases with similar 6q interstitial deletions. It is interesting to note the clinical similarities between some patients with interstitial deletions of 6q16 or q21 bands and patients with Prader-Willi syndrome (PWS) and it may help to keep in mind cytogenetic studies of patients with some PWS findings. 24 refs., 3 figs., 2 tabs.

Sponsoring Organization:
USDOE
OSTI ID:
91130
Journal Information:
American Journal of Medical Genetics, Journal Name: American Journal of Medical Genetics Journal Issue: 3 Vol. 55; ISSN 0148-7299; ISSN AJMGDA
Country of Publication:
United States
Language:
English