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Unique de novo interstitial deletion of chromosome 17, del(17) (q23.2q24.3) in a female newborn with multiple congenital anomalies

Journal Article · · American Journal of Medical Genetics
; ;  [1]
  1. Baylor College of Medicine and the Texas Children`s Hospital, Houston, TX (United States); and others

We describe a newborn with a novel interstitial deletion of the long arm of chromosome 17 (del(17) (q23.2q24.3)) who died on day of life 17 during a recurrent apneic episode. Her phenotype included severe growth retardation, multiple facial anomalies, maldeveloped oralpharyngeal structures, and digital and widespread skeletal anomalies. This patient`s phenotype was compared to two other reported patients with deletion 17q with minor clinical overlap consistent with a unique deletion. 9 refs., 2 figs.

Sponsoring Organization:
USDOE
OSTI ID:
91097
Journal Information:
American Journal of Medical Genetics, Journal Name: American Journal of Medical Genetics Journal Issue: 1 Vol. 55; ISSN 0148-7299; ISSN AJMGDA
Country of Publication:
United States
Language:
English

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