Effects of hydration water on protein methyl group dynamics insolution
Journal Article
·
· Physical Review E
OSTI ID:910600
Elastic and quasielastic neutron scattering experiments have been used to investigate the dynamics of methyl groups in a protein-model hydrophobic peptide in solution. The results suggest that, when the hydrophobic side chains are hydrated by a single hydration water layer, the only allowed motions are confined and attributed to librational and rotational movement associated with the methyl groups. They provide unique experimental evidence that the structural and dynamical properties of the interfacial water strongly influence the side-chain dynamics and the activation of diffusive motion.
- Research Organization:
- COLLABORATION - Institut LaueLangevin/France
- DOE Contract Number:
- DE-AC02-05CH11231
- OSTI ID:
- 910600
- Report Number(s):
- LBNL-63261; PLEEE8; TRN: US0704270
- Journal Information:
- Physical Review E, Vol. 75, Issue 4pt1; Related Information: Journal Publication Date: 04/2007; ISSN 1063-651X
- Country of Publication:
- United States
- Language:
- English
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