Analysis of allelic variation of the apolipoprotein B hypervariable locus in the Bashkir and Komi populations
Journal Article
·
· Russian Journal of Genetics
OSTI ID:91054
- Bashkir Scientific Center, Ufa (Russian Federation); and others
Allelic variation of the hypervariable apolipoprotein B gene locus (APOB) in three groups of the Bashkir population and in the Komi population was analyzed. Among 219 individuals studied, 13 allelic variants were identified with a number of repeats ranging from 28 to 52. The frequency of alleles varied from 0.01 to 0.51 with the mean heterozygosity index being 0.66 in the Bashkir population and 0.74 in the Komi one. Considerable difference in the frequency distribution of the APOB loci genotypes between the Bashkir and Komi populations was observed, and the distribution patterns for Bashkirs from Abzelilovskii and Ilishevskii raions deviated from the Hardy-Weinberg equilibrium. The genetic distance between the Bashkir and Komi populations calculated on the basis of allele frequencies at the hypervariable APOB gene locus corresponded to the expected degree similarity of the population studied. Thus, this locus can be recommended as an informative marker for studying the gene pool and genetic processes in the populations because of the high level of its polymorphism and the heterozygosity in the populations. 19 refs., 1 fig., 4 tabs.
- OSTI ID:
- 91054
- Journal Information:
- Russian Journal of Genetics, Journal Name: Russian Journal of Genetics Journal Issue: 7 Vol. 31; ISSN RJGEEQ; ISSN 1022-7954
- Country of Publication:
- United States
- Language:
- English
Similar Records
Characteristics of polymorphism at a VNTR locus 3[prime] to the apolipoprotein B gene in five human populations
Allelic variants of the genes of apolipoproteins B and CII in patients with coronary heart disease and in healthy individuals from the Moscow population
Intra-and inter-population genetic diversity at the HLA-DQA1 locus and their implications for parentage analysis and human identification
Journal Article
·
Mon Nov 30 23:00:00 EST 1992
· American Journal of Human Genetics; (United States)
·
OSTI ID:6697807
Allelic variants of the genes of apolipoproteins B and CII in patients with coronary heart disease and in healthy individuals from the Moscow population
Journal Article
·
Sat Jul 01 00:00:00 EDT 1995
· Russian Journal of Genetics
·
OSTI ID:91055
Intra-and inter-population genetic diversity at the HLA-DQA1 locus and their implications for parentage analysis and human identification
Journal Article
·
Thu Sep 01 00:00:00 EDT 1994
· American Journal of Human Genetics
·
OSTI ID:133936