Glycoprotein synthesis
Abstract
Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
- Inventors:
-
- La Jolla, CA
- San Diego, CA
- Publication Date:
- Research Org.:
- The Scripps Research Institute (La Jolla, CA)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 907753
- Patent Number(s):
- 7,199,222
- Application Number:
- 11/093,597
- Assignee:
- The Scripps Research Institute (La Jolla, CA) OSTI
- DOE Contract Number:
- FG03-00ER45812
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Shultz, Peter G, Wang, Lei, and Zhang, Zhiwen. Glycoprotein synthesis. United States: N. p., 2007.
Web.
Shultz, Peter G, Wang, Lei, & Zhang, Zhiwen. Glycoprotein synthesis. United States.
Shultz, Peter G, Wang, Lei, and Zhang, Zhiwen. Tue .
"Glycoprotein synthesis". United States.
doi:. https://www.osti.gov/servlets/purl/907753.
@article{osti_907753,
title = {Glycoprotein synthesis},
author = {Shultz, Peter G and Wang, Lei and Zhang, Zhiwen},
abstractNote = {Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 03 00:00:00 EDT 2007},
month = {Tue Apr 03 00:00:00 EDT 2007}
}
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