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Structure of the LDL receptor extracellular domain at endosomalpH

Journal Article · · Science
OSTI ID:891803

The structure of the low-density lipoprotein receptor extracellular portion has been determined. The document proposes a mechanism for the release of lipoprotein in the endosome. Without this release, the mechanism of receptor recycling cannot function.

Research Organization:
COLLABORATION - U. of Texas Southwest Med.Ctr
DOE Contract Number:
AC02-05CH11231
OSTI ID:
891803
Report Number(s):
LBNL--51933
Journal Information:
Science, Journal Name: Science Vol. 298; ISSN 0193-4511; ISSN SCEHDK
Country of Publication:
United States
Language:
English

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