The National Center for Biomedical Ontology: Advancing Biomedicinethrough Structured Organization of Scientific Knowledge

Journal Article · Mon Jan 23 04:00:00 EST 2006 · OMICS: A Journal of Integrative Biology

DOI:https://doi.org/10.1089/omi.2006.10.185· OSTI ID:890687

Rubin, Daniel L; Lewis, Suzanna E; Mungall, Chris J; Misra, Sima; Westerfield, Monte; Ashburner, Michael; Sim, Ida; Chute, Christopher G; Solbrig, Harold; Storey, Margaret-Anne; Smith, Barry; Day-Richter, John; Noy, Natalya F; Musen, Mark A

The National Center for Biomedical Ontology(http://bioontology.org) is a consortium that comprises leadinginformaticians, biologists, clinicians, and ontologists funded by the NIHRoadmap to develop innovative technology and methods that allowscientists to record, manage, and disseminate biomedical information andknowledge in machine-processable form. The goals of the Center are: (1)to help unify the divergent and isolated efforts in ontology developmentby promoting high quality open-source, standards-based tools to create,manage, and use ontologies, (2) to create new software tools so thatscientists can use ontologies to annotate and analyze biomedical data,(3) to provide a national resource for the ongoing evaluation,integration, and evolution of biomedical ontologies and associated toolsand theories in the context of driving biomedical projects (DBPs), and(4) to disseminate the tools and resources of the Center and to identify,evaluate, and communicate best practices of ontology development to thebiomedical community. The Center is working toward these objectives byproviding tools to develop ontologies and to annotate experimental data,and by developing resources to integrate and relate existing ontologiesas well as by creating repositories of biomedical data that are annotatedusing those ontologies. The Center is providing training workshops inontology design, development, and usage, and is also pursuing research inontology evaluation, quality, and use of ontologies to promote scientificdiscovery. Through the research activities within the Center,collaborations with the DBPs, and interactions with the biomedicalcommunity, our goal is to help scientists to work more effectively in thee-science paradigm, enhancing experiment design, experiment execution,data analysis, information synthesis, hypothesis generation and testing,and understand human disease.

• Research Organization: Ernest Orlando Lawrence Berkeley NationalLaboratory, Berkeley, CA (US)
• Sponsoring Organization: USDOE; National Institutes of Health. National Center forBiomedical Ontology Grant U54 HG004028
• DOE Contract Number: AC02-05CH11231
• OSTI ID: 890687
• Report Number(s): LBNL--60314; BnR: 600305000
• Journal Information: OMICS: A Journal of Integrative Biology, Journal Name: OMICS: A Journal of Integrative Biology Journal Issue: 2 Vol. 10
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
99 GENERAL AND MISCELLANEOUS
Biomedicine ontologies bioinformatics