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Title: Interactive protein manipulation

Abstract

We describe an interactive visualization and modeling program for the creation of protein structures ''from scratch''. The input to our program is an amino acid sequence -decoded from a gene- and a sequence of predicted secondary structure types for each amino acid-provided by external structure prediction programs. Our program can be used in the set-up phase of a protein structure prediction process; the structures created with it serve as input for a subsequent global internal energy minimization, or another method of protein structure prediction. Our program supports basic visualization methods for protein structures, interactive manipulation based on inverse kinematics, and visualization guides to aid a user in creating ''good'' initial structures.

Authors:
Publication Date:
Research Org.:
Ernest Orlando Lawrence Berkeley NationalLaboratory, Berkeley, CA (US)
Sponsoring Org.:
USDOE Director. Office of Science. Office of AdvancedScientific Computing Research; National Science Foundation ContractACI-9624034 and ACI 9982251, National Institutes of Health Contract P20MH60975-06A2
OSTI Identifier:
886595
Report Number(s):
LBNL-52414
R&D Project: K11107; BnR: KJ0101030; TRN: US0603968
DOE Contract Number:  
DE-AC02-05CH11231
Resource Type:
Conference
Resource Relation:
Conference: IEEE Visualization 2003, Seattle, WA, September2003
Country of Publication:
United States
Language:
English
Subject:
12 MANAGEMENT OF RADIOACTIVE WASTES, AND NON-RADIOACTIVE WASTES FROM NUCLEAR FACILITIES; 60 APPLIED LIFE SCIENCES; AMINO ACID SEQUENCE; FORECASTING; MINIMIZATION; PROTEIN STRUCTURE; PROTEINS; SIMULATION; protein manipulation inverse kinematics

Citation Formats

SNCrivelli@lbl.gov. Interactive protein manipulation. United States: N. p., 2003. Web.
SNCrivelli@lbl.gov. Interactive protein manipulation. United States.
SNCrivelli@lbl.gov. Tue . "Interactive protein manipulation". United States. https://www.osti.gov/servlets/purl/886595.
@article{osti_886595,
title = {Interactive protein manipulation},
author = {SNCrivelli@lbl.gov},
abstractNote = {We describe an interactive visualization and modeling program for the creation of protein structures ''from scratch''. The input to our program is an amino acid sequence -decoded from a gene- and a sequence of predicted secondary structure types for each amino acid-provided by external structure prediction programs. Our program can be used in the set-up phase of a protein structure prediction process; the structures created with it serve as input for a subsequent global internal energy minimization, or another method of protein structure prediction. Our program supports basic visualization methods for protein structures, interactive manipulation based on inverse kinematics, and visualization guides to aid a user in creating ''good'' initial structures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 01 00:00:00 EDT 2003},
month = {Tue Jul 01 00:00:00 EDT 2003}
}

Conference:
Other availability
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