skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Positron emission mammography with tomographic acquisition using dual planar detectors: initial evaluations

Abstract

Positron emission mammography (PEM) with tomographic acquisition using dual planar detectors rotating about the breast can obtain complete angular sampling and has the potential to improve activity estimation compared with PEM using stationary detectors. PEM tomography (PEMT) was compared with stationary PEM for point source and compressed breast phantom studies performed with a compact dual detector system. The acquisition geometries were appropriate for the target application of PEM guidance of stereotactic core biopsy. Images were reconstructed with a three-dimensional iterative maximum likelihood expectation maximization algorithm. PEMT eliminated blurring normal to the detectors seen with stationary PEM. Depth of interaction effects distorted the shape of the point spread functions for PEMT as the angular range from normal incidence of lines of response used in image reconstruction increased. Streak artifacts in PEMT for large detector rotation increments led to the development of an expression for the maximum rotation increment that maintains complete angular sampling. Studies with a compressed breast phantom were used to investigate contrast and signal-to-noise ratio (SNR) trade-offs for different sized spherical tumor models. PEMT and PEM both had advantages depending on lesion size and detector separation. The most appropriate acquisition method for specific detection or quantitation tasks requires additionalmore » investigation.« less

Authors:
; ; ;
Publication Date:
Research Org.:
Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA
Sponsoring Org.:
USDOE - Office of Energy Research (ER)
OSTI Identifier:
882455
Report Number(s):
JLAB-PHY-03-221; DOE/ER/40150-3876
Journal ID: ISSN 0031-9155; PHMBA7; TRN: US0603223
DOE Contract Number:  
AC05-84ER40150
Resource Type:
Journal Article
Journal Name:
Physics in Medicine and Biology
Additional Journal Information:
Journal Volume: 49; Journal ID: ISSN 0031-9155
Country of Publication:
United States
Language:
English
Subject:
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; BIOPSY; DETECTION; MAMMARY GLANDS; NEOPLASMS; PHANTOMS; POINT SOURCES; POSITRONS; ROTATION; SAMPLING; SHAPE; SIGNAL-TO-NOISE RATIO; TARGETS; TOMOGRAPHY

Citation Formats

Mark F Smith, Raymond R Raylman, Stan Majewski, and Andrew G Weisenberger. Positron emission mammography with tomographic acquisition using dual planar detectors: initial evaluations. United States: N. p., 2004. Web. doi:10.1088/0031-9155/49/11/022.
Mark F Smith, Raymond R Raylman, Stan Majewski, & Andrew G Weisenberger. Positron emission mammography with tomographic acquisition using dual planar detectors: initial evaluations. United States. doi:10.1088/0031-9155/49/11/022.
Mark F Smith, Raymond R Raylman, Stan Majewski, and Andrew G Weisenberger. Sat . "Positron emission mammography with tomographic acquisition using dual planar detectors: initial evaluations". United States. doi:10.1088/0031-9155/49/11/022. https://www.osti.gov/servlets/purl/882455.
@article{osti_882455,
title = {Positron emission mammography with tomographic acquisition using dual planar detectors: initial evaluations},
author = {Mark F Smith and Raymond R Raylman and Stan Majewski and Andrew G Weisenberger},
abstractNote = {Positron emission mammography (PEM) with tomographic acquisition using dual planar detectors rotating about the breast can obtain complete angular sampling and has the potential to improve activity estimation compared with PEM using stationary detectors. PEM tomography (PEMT) was compared with stationary PEM for point source and compressed breast phantom studies performed with a compact dual detector system. The acquisition geometries were appropriate for the target application of PEM guidance of stereotactic core biopsy. Images were reconstructed with a three-dimensional iterative maximum likelihood expectation maximization algorithm. PEMT eliminated blurring normal to the detectors seen with stationary PEM. Depth of interaction effects distorted the shape of the point spread functions for PEMT as the angular range from normal incidence of lines of response used in image reconstruction increased. Streak artifacts in PEMT for large detector rotation increments led to the development of an expression for the maximum rotation increment that maintains complete angular sampling. Studies with a compressed breast phantom were used to investigate contrast and signal-to-noise ratio (SNR) trade-offs for different sized spherical tumor models. PEMT and PEM both had advantages depending on lesion size and detector separation. The most appropriate acquisition method for specific detection or quantitation tasks requires additional investigation.},
doi = {10.1088/0031-9155/49/11/022},
journal = {Physics in Medicine and Biology},
issn = {0031-9155},
number = ,
volume = 49,
place = {United States},
year = {2004},
month = {5}
}