Therapeutic tin-117m compositions

Patent · Tue Dec 31 23:00:00 EST 2002

OSTI ID:875037

Srivastava, Suresh C ^[1]; Meinken, George E ^[2]; Mausner, Leonard F ^[3]; Atkins, Harold L ^[1]

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1. Setauket, NY
2. Middle Island, NY
3. Stony Brook, NY

The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients.

• Research Organization: ASSOC UNIVERSITIES INC
• DOE Contract Number: AC02-76CH00016
• Assignee: Brookhaven Science Associates LLC (Upton, NY)
• Patent Number(s): US 6517810
• OSTI ID: 875037
• Country of Publication: United States
• Language: English

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