Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants

Somerville, Chris; van de Loo, Frank

Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants

Patent · Mon Dec 31 23:00:00 EST 2001

OSTI ID:874653

Somerville, Chris ^[1]; van de Loo, Frank ^[2]

Portola Valley, CA
Lexington, KY

The present invention relates to the identification of nucleic acid sequences and constructs, and methods related thereto, and the use of these sequences and constructs to produce genetically modified plants for the purpose of altering the composition of plant oils, waxes and related compounds.

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Research Organization:: Carnegie Institute of Washington (US)

DOE Contract Number:: FG02-94ER20133

Assignee:: Carnegie Institution of Washington (Washington, DC)

Patent Number(s):: US 6433250

OSTI ID:: 874653

Country of Publication:: United States

Language:: English

References (48)

Signal sequences von Heijne, Gunnar Journal of Molecular Biology, Vol. 184, Issue 1 https://doi.org/10.1016/0022-2836(85)90046-4	journal	July 1985
Characterization of two divergent β-tubulin genes from Colletotrichum graminicola Panaccione, Daniel G.; Hanau, Robert M. Gene, Vol. 86, Issue 2 https://doi.org/10.1016/0378-1119(90)90275-V	journal	February 1990
The promoter of TL-DNA gene 5 controls the tissue-specific expression of chimaeric genes carried by a novel type of Agrobacterium binary vector Koncz, Csaba; Schell, Jeff MGG Molecular & General Genetics, Vol. 204, Issue 3 https://doi.org/10.1007/BF00331014	journal	September 1986
Octopine Ti-plasmid deletion mutants of Agrobacterium tumefaciens with emphasis on the right side of the T-region Ooms, Gert; Hooykaas, Paul J. J.; Van Veen, Ron J. M. Plasmid, Vol. 7, Issue 1 https://doi.org/10.1016/0147-619X(82)90023-3	journal	January 1982
The Biosynthesis of Ricinoleic Acid by Claviceps purpurea Morris, L. J.; Hall, S. W.; James, A. T. Biochemical Journal, Vol. 100, Issue 3 https://doi.org/10.1042/bj1000029C	journal	September 1966
Effective vectors for transformation, expression of heterologous genes, and assaying transposon excision in transgenic plants Jones, Jonathan D. G.; Shlumukov, L.; Carland, F. Transgenic Research, Vol. 1, Issue 6 https://doi.org/10.1007/BF02525170	journal	November 1992
Evidence for cytochrome b5 as an electron donor in ricinoleic acid biosynthesis in microsomal preparations from developing castor bean (Ricinus communis L.) Smith, M. A.; Jonsson, L.; Stymne, S. Biochemical Journal, Vol. 287, Issue 1 https://doi.org/10.1042/bj2870141	journal	October 1992
[19] Isolation of multigene families and determination of homologies by filter hybridization methods Beltz, Gerald A.; Jacobs, Kenneth A.; Eickbush, Thomas H. Recombinant DNA Part B https://doi.org/10.1016/0076-6879(83)00061-0	book	January 1983
A Comparison of the Metabolic Fate of Fatty Acids of Different Chain Lengths in Developing Oilseeds Battey, James F.; Ohlrogge, John B. Plant Physiology, Vol. 90, Issue 3 https://doi.org/10.1104/pp.90.3.835	journal	July 1989
Occurrence of ricinoleic acid in submerged cultures of variousClaviceps sp. Křen, V.; Řezanka, T.; Řeháček, Z. Experientia, Vol. 41, Issue 11 https://doi.org/10.1007/BF01950045	journal	November 1985
Rapid isolation of high molecular weight plant DNA Murray, M. G.; Thompson, W. F. Nucleic Acids Research, Vol. 8, Issue 19 https://doi.org/10.1093/nar/8.19.4321	journal	January 1980
The mechanism of ricinoleic acid biosynthesis in Ricinuscommunis seeds Morris, L. J. Biochemical and Biophysical Research Communications, Vol. 29, Issue 3 https://doi.org/10.1016/0006-291X(67)90454-8	journal	November 1967
Formation of oil in the seed of Ricinus Communis l. Canvin, David T. Canadian Journal of Biochemistry and Physiology, Vol. 41, Issue 9 https://doi.org/10.1139/o63-214	journal	September 1963
Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species. Gould, S. J.; Subramani, S.; Scheffler, I. E. Proceedings of the National Academy of Sciences, Vol. 86, Issue 6 https://doi.org/10.1073/pnas.86.6.1934	journal	March 1989
Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis. Okuley, J.; Lightner, J.; Feldmann, K. The Plant Cell, Vol. 6, Issue 1 https://doi.org/10.1105/tpc.6.1.147	journal	January 1994
Glycerolipid Synthesis: Biochemistry and Regulation Browse, J.; Somerville, C. Annual Review of Plant Physiology and Plant Molecular Biology, Vol. 42, Issue 1 https://doi.org/10.1146/annurev.pp.42.060191.002343	journal	June 1991
A bifunctional oleate 12‐hydroxylase: desaturase from Lesquerella fendleri Broun, Pierre; Boddupalli, Sekhar; Somerville, Chris The Plant Journal, Vol. 13, Issue 2 https://doi.org/10.1046/j.1365-313X.1998.00023.x	journal	January 1998
Expression of the ?-subunit of ?-conglycinin in seeds of transgenic plants Bray, Elizabeth A.; Naito, Satoshi; Pan, Nai-Sui Planta, Vol. 172, Issue 3 https://doi.org/10.1007/BF00398665	journal	November 1987
Accumulation of Ricinoleic, Lesquerolic, and Densipolic Acids in Seeds of Transgenic Arabidopsis Plants That Express a Fatty Acyl Hydroxylase cDNA from Castor Bean Broun, P.; Somerville, C. Plant Physiology, Vol. 113, Issue 3 https://doi.org/10.1104/pp.113.3.933	journal	March 1997
The Biosynthesis of Ricinoleic acid James, At; Hadaway, Hc; Webb, Jpw Biochemical Journal, Vol. 95, Issue 2 https://doi.org/10.1042/bj0950448	journal	May 1965
The role of cytochrome b5 in Δ12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.) Kearns, Ellen V.; Hugly, Suzanne; Somerville, Chris R. Archives of Biochemistry and Biophysics, Vol. 284, Issue 2 https://doi.org/10.1016/0003-9861(91)90319-E	journal	February 1991
An oleate 12-hydroxylase from Ricinus communis L. is a fatty acyl desaturase homolog. van de Loo, F. J.; Broun, P.; Turner, S. Proceedings of the National Academy of Sciences, Vol. 92, Issue 15 https://doi.org/10.1073/pnas.92.15.6743	journal	July 1995
Plasmid [omega]-3 Fatty Acid Desaturase cDNA from Ricinus communis van de Loo, F. J.; Somerville, C. Plant Physiology, Vol. 105, Issue 1 https://doi.org/10.1104/pp.105.1.443	journal	May 1994
Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis Arondel, V.; Lemieux, B.; Hwang, I. Science, Vol. 258, Issue 5086 https://doi.org/10.1126/science.1455229	journal	November 1992
Recent Studies of the Enzymic Synthesis of Ricinoleic Acid by Developing Castor Beans Moreau, Robert A.; Stumpf, Paul K. Plant Physiology, Vol. 67, Issue 4 https://doi.org/10.1104/pp.67.4.672	journal	April 1981
Construction and sequence of cDNA for rat liver stearyl coenzyme A desaturase. Thiede, M. A.; Ozols, J.; Strittmatter, P. Journal of Biological Chemistry, Vol. 261, Issue 28 https://doi.org/10.1016/S0021-9258(18)69295-6	journal	October 1986
Fat Metabolism in Higher Plants Galliard, T.; Stumpf, P. K. Journal of Biological Chemistry, Vol. 241, Issue 24 https://doi.org/10.1016/S0021-9258(18)96344-1	journal	December 1966
Cloning of Higher Plant [omega]-3 Fatty Acid Desaturases Yadav, N. S.; Wierzbicki, A.; Aegerter, M. Plant Physiology, Vol. 103, Issue 2 https://doi.org/10.1104/pp.103.2.467	journal	October 1993
In Planta Agrobacterium-Mediated Transformation of Adult Arabidopsis thaliana Plants by Vacuum Infiltration Bechtold, N.; Bouchez, D.; Potrykus, Ingo Gene Transfer to Plants, p. 19-23 https://doi.org/10.1007/978-3-642-79247-2_3	book	January 1995
Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase. Miquel, M.; Browse, J. Journal of Biological Chemistry, Vol. 267, Issue 3 https://doi.org/10.1016/S0021-9258(18)45974-1	journal	January 1992
Phospholipids of palash ( Butea monosperma ), papaya ( Carica papaya ), jangli badam ( Sterculia foetida ), coriander ( Coriandrum sativum ) and carrot ( Daucus carota ) seeds Prasad, R. B. N.; Rao, Y. Nagender; Rao, S. Venkob Journal of the American Oil Chemists' Society, Vol. 64, Issue 10 https://doi.org/10.1007/BF02636993	journal	October 1987
Ricinoleic acid biosynthesis and triacylglycerol assembly in microsomal preparations from developing castor-bean (Ricinus communis) endosperm Bafor, M.; Smith, M. A.; Jonsson, L. Biochemical Journal, Vol. 280, Issue 2 https://doi.org/10.1042/bj2800507	journal	December 1991
Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Ditta, G.; Stanfield, S.; Corbin, D. Proceedings of the National Academy of Sciences, Vol. 77, Issue 12 https://doi.org/10.1073/pnas.77.12.7347	journal	December 1980
The specificity of fatty acid desaturases and hydroxylases Howling, D.; Morris, L. J.; Gurr, M. I. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 260, Issue 1 https://doi.org/10.1016/0005-2760(72)90068-9	journal	January 1972
Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids Broun, Pierre; Shanklin, John; Whittle, Ed Science, Vol. 282, Issue 5392, p. 1315-1317 https://doi.org/10.1126/science.282.5392.1315	journal	November 1998
A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana. Iba, K.; Gibson, S.; Nishiuchi, T. Journal of Biological Chemistry, Vol. 268, Issue 32 https://doi.org/10.1016/S0021-9258(20)80498-0	journal	November 1993
Seed development in Ricinus communis (castor bean). I. Descriptive morphology Greenwood, J. S.; Bewley, J. D. Canadian Journal of Botany, Vol. 60, Issue 9 https://doi.org/10.1139/b82-222	journal	September 1982
The Pseudomonas oleovorans alkane hydroxylase gene Kok, M.; Oldenhuis, R.; van der Linden, M. P. G. Journal of Biological Chemistry, Vol. 264, Issue 10 https://doi.org/10.1016/S0021-9258(18)83564-5	journal	April 1989
How and Why Do Plants Inactivate Homologous (Trans)genes? Matzke, M. A.; Matzke, Ajm. Plant Physiology, Vol. 107, Issue 3 https://doi.org/10.1104/pp.107.3.679	journal	March 1995
Mechanisms and stereochemistry in fatty acid metabolism Morris, L. J. Biochemical Journal, Vol. 118, Issue 5 https://doi.org/10.1042/bj1180681g	journal	August 1970
Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system. Suzuki, M.; Hayakawa, T.; Shaw, J. P. Journal of Bacteriology, Vol. 173, Issue 5 https://doi.org/10.1128/JB.173.5.1690-1695.1991	journal	January 1991
Basic local alignment search tool Altschul, Stephen F.; Gish, Warren; Miller, Webb Journal of Molecular Biology, Vol. 215, Issue 3, p. 403-410 https://doi.org/10.1016/S0022-2836(05)80360-2	journal	October 1990
Modification of Plant Lipid Synthesis Topfer, R.; Martini, N.; Schell, J. Science, Vol. 268, Issue 5211 https://doi.org/10.1126/science.268.5211.681	journal	May 1995
Design of New Plant Products: Engineering of Fatty Acid Metabolism Ohlrogge, J. B. Plant Physiology, Vol. 104, Issue 3 https://doi.org/10.1104/pp.104.3.821	journal	March 1994
Cloning of a Temperature-Regulated Gene Encoding a Chloroplast [omega]-3 Desaturase from Arabidopsis thaliana Gibson, S.; Arondel, V.; Iba, K. Plant Physiology, Vol. 106, Issue 4 https://doi.org/10.1104/pp.106.4.1615	journal	December 1994
Analysis of oil and meal from Lesquerella fendleri seed Carlson, K. D.; Chaudhry, A.; Bagby, M. O. Journal of the American Oil Chemists' Society, Vol. 67, Issue 7 https://doi.org/10.1007/BF02638957	journal	July 1990
DST sequences, highly conserved among plant SAUR genes, target reporter transcripts for rapid decay in tobacco. Newman, T. C.; Ohme-Takagi, M.; Taylor, C. B. The Plant Cell, Vol. 5, Issue 6 https://doi.org/10.1105/tpc.5.6.701	journal	June 1993
Eight Histidine Residues Are Catalytically Essential in a Membrane-Associated Iron Enzyme, Stearoyl-CoA Desaturase, and Are Conserved in Alkane Hydroxylase and Xylene Monooxygenase Shanklin, John; Whittle, Edward; Fox, Brian G. Biochemistry, Vol. 33, Issue 43 https://doi.org/10.1021/bi00209a009	journal	January 1994

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Related Subjects

/800/435/
acid
acid sequence
acids
acyl
altering
composition
compounds
constructs
derivatives
fatty
fatty acid
fatty acyl
genetically
hydroxylases
hydroxylated
identification
methods
methods related
modified
nucleic
nucleic acid
oils
plant
plant fatty
plants
produce
purpose
related
relates
sequences
waxes

Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants

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References (48)

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