T-load microchannel array and fabrication method

Patent · Sat Jan 01 00:00:00 EST 2000

OSTI ID:873190

Swierkowski, Stefan P ^[1]

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1. Livermore, CA

A three-dimensional (3-D) T-load for planar microchannel arrays for electrophoresis, for example, which enables sample injection directly onto a plane perpendicular to the microchannels' axis, at their ends. This is accomplished by forming input wells that extend beyond the ends of the microchannel thereby eliminating the right angle connection from the input well into the end of the microchannel. In addition, the T-load input well eases the placement of electrode in or adjacent the well and thus enables very efficient reproducible electrokinetic (ek) injection. The T-load input well eliminates the prior input well/microchannel alignment concerns, since the input well can be drilled after the top and bottom microchannel plates are bonded together. The T-load input well may extend partially or entirely through the bottom microchannel plate which enables more efficient gel and solution flushing, and also enables placement of multiple electrodes to assist in the ek sample injection.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
• DOE Contract Number: W-7405-ENG-48
• Assignee: Regents of University of California (Oakland, CA)
• Patent Number(s): US 6110332
• OSTI ID: 873190
• Country of Publication: United States
• Language: English

Related Subjects

t-load
microchannel
array
fabrication
method
three-dimensional
3-d
planar
arrays
electrophoresis
example
enables
sample
injection
directly
plane
perpendicular
microchannels
axis
accomplished
forming
input
extend
eliminating
angle
connection
addition
eases
placement
electrode
adjacent
efficient
reproducible
electrokinetic
ek
eliminates
prior
alignment
concerns
drilled
top
bottom
plates
bonded
partially
entirely
plate
solution
flushing
multiple
electrodes
assist
channel plate
multiple electrodes
fabrication method
plane perpendicular
microchannel plate
multiple electrode
sample injection
microchannel plates
microchannel array
injection directly
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