Micro-sonicator for spore lysis

Patent · Fri Dec 31 23:00:00 EST 1999

OSTI ID:873141

Miles, Robin R ^[1]; Belgrader, Phillip ^[2]; Nasarabadi, Shanavaz L ^[1]

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1. Livermore, CA
2. Manteca, CA

A micro-sonicator for spore lysis. Using micromachining technology, the micro-sonicator uses ultrasonic excitation of spores to perform spore and cell lysis. The micro-sonicator comprises a container with a cavity therein for retaining the sample in an ultrasonic transmission medium, the cavity being closed by a silicon membrane to which an electrode and piezoelectric material are attached, with the electrode and piezoelectric material being electrically connected to an AC signal generator which causes the membrane to flex and vibrate at the frequency of the applied voltage.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA
• DOE Contract Number: W-7405-ENG-48
• Assignee: Regents of University of California (Oakland, CA)
• Patent Number(s): US 6100084
• OSTI ID: 873141
• Country of Publication: United States
• Language: English

Related Subjects

/435/241/366/
applied
applied voltage
attached
causes
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closed
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connected
container
electrically
electrically connected
electrode
excitation
flex
frequency
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lysis
material
medium
membrane
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micromachining
perform
piezoelectric
piezoelectric material
retaining
sample
signal
signal generator
silicon
spore
spore lysis
spores
technology
therein
transmission
transmission medium
ultrasonic
ultrasonic transmission
vibrate
voltage