Microfabricated therapeutic actuators

Patent · Thu Dec 31 23:00:00 EST 1998

OSTI ID:872326

Lee, Abraham P ^[1]; Northrup, M Allen ^[2]; Ciarlo, Dino R ^[3]; Krulevitch, Peter A ^[4]; Benett, William J ^[3]

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1. Walnut Creek, CA
2. Berkeley, CA
3. Livermore, CA
4. Pleasanton, CA

Microfabricated therapeutic actuators are fabricated using a shape memory polymer (SMP), a polyurethane-based material that undergoes a phase transformation at a specified temperature (Tg). At a temperature above temperature Tg material is soft and can be easily reshaped into another configuration. As the temperature is lowered below temperature Tg the new shape is fixed and locked in as long as the material stays below temperature Tg. Upon reheating the material to a temperature above Tg, the material will return to its original shape. By the use of such SMP material, SMP microtubing can be used as a release actuator for the delivery of embolic coils through catheters into aneurysms, for example. The microtubing can be manufactured in various sizes and the phase change temperature Tg is determinate for an intended temperature target and intended use.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA
• DOE Contract Number: W-7405-ENG-48
• Assignee: Regents of University of California (Oakland, CA)
• Patent Number(s): US 5911737
• OSTI ID: 872326
• Country of Publication: United States
• Language: English

Related Subjects

/606/128/
actuator
actuators
aneurysms
below
below temperature
catheters
change
change temperature
coils
configuration
delivery
determinate
easily
easily reshaped
embolic
embolic coil
embolic coils
example
fabricated
fixed
intended
intended temperature
locked
lowered
lowered below
manufactured
material
material stays
memory
memory polymer
microfabricated
microfabricated therapeutic
microtubing
original
original shape
phase
phase change
phase transformation
polymer
polyurethane-based
polyurethane-based material
reheating
release
release actuator
reshaped
return
shape
shape memory
sizes
smp
smp material
smp microtubing
soft
specified
specified temperature
stays
stays below
target
temperature
temperature target
temperature tg
tg
tg material
therapeutic
therapeutic actuator
therapeutic actuators
transformation
undergoes
various
various sizes