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Accelerator-based neutron source for boron neutron capture therapy (BNCT) and method

Patent ·
OSTI ID:872288
 [1];  [1];  [1];  [1]
  1. Idaho Falls, ID
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A source for boron neutron capture therapy (BNCT) comprises a body of photoneutron emitter that includes heavy water and is closely surrounded in heat-imparting relationship by target material; one or more electron linear accelerators for supplying electron radiation having energy of substantially 2 to 10 MeV and for impinging such radiation on the target material, whereby photoneutrons are produced and heat is absorbed from the target material by the body of photoneutron emitter. The heavy water is circulated through a cooling arrangement to remove heat. A tank, desirably cylindrical or spherical, contains the heavy water, and a desired number of the electron accelerators circumferentially surround the tank and the target material as preferably made up of thin plates of metallic tungsten. Neutrons generated within the tank are passed through a surrounding region containing neutron filtering and moderating materials and through neutron delimiting structure to produce a beam or beams of epithermal neutrons normally having a minimum flux intensity level of 1.0.times.10.sup.9 neutrons per square centimeter per second. Such beam or beams of epithermal neutrons are passed through gamma ray attenuating material to provide the required epithermal neutrons for BNCT use.

Research Organization:
Idaho National Engineering and Environmental Laboratory, Idaho Falls, ID
DOE Contract Number:
AC07-94ID13223
Assignee:
Lockheed Martin Idaho Technologies Company (Idaho Falls, ID)
Patent Number(s):
US 5903622
OSTI ID:
872288
Country of Publication:
United States
Language:
English

References (6)

Linear accelerator neutron source for neutron scattering journal July 1974
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy journal July 1992
Epithermal BNCT Neutron Beam Design for a Triga II Reactor book January 1993
A novel way of producing 38S journal February 1973
A Design Study of the Neutron Irradiation Facility for Boron Neutron Capture Therapy journal December 1981
A dynamic “loop”—target for the incyclotron production of 18F by the 16O (α, d)16F reaction on water journal February 1973

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