Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same

Katti, Kattesh V; Berning, Douglas E; Volkert, Wynn A; Ketring, Alan R

Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same

Patent · Wed Dec 31 23:00:00 EST 1997

OSTI ID:872011

Katti, Kattesh V ^[1]; Berning, Douglas E ^[1]; Volkert, Wynn A ^[1]; Ketring, Alan R ^[1]

Columbia, MO

A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.

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Research Organization:: University of Missouri

DOE Contract Number:: FG02-89ER60875

Assignee:: Curators of University of Missouri (Columbia, MO)

Patent Number(s):: US 5843993

OSTI ID:: 872011

Country of Publication:: United States

Language:: English

References (19)

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Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same

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References (19)

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