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Cell-targeted lytic pore-forming agents

Patent ·
OSTI ID:871879
 [1];  [2]
  1. Grafton, MA
  2. Auburn, MA
+ Show Author Affiliations
A chimeric compound that contains a cell-specific ligand linked to a pore-forming agent capable of lysing a cell.
Research Organization:
Worcester Foundation
DOE Contract Number:
FG02-90ER20018
Assignee:
Worcester Foundation for Experimental Biology (Shrewsbury, MA)
Patent Number(s):
US 5817771
OSTI ID:
871879
Country of Publication:
United States
Language:
English

References (8)

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46. journal January 1984
Staphylococcal alpha toxin — recent advances journal January 1988
Problems in the investigational study and clinical use of cancer immunotherapy journal January 1990
Therapeutic antibodies — the coming of age journal February 1993
Molecular design gets into a hole journal February 1992
A Pore-forming protein with a protease-activated trigger journal January 1994
Immunotoxins journal December 1986
Secondary structure and assembly mechanism of an oligomeric channel protein journal April 1985

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Related Subjects

/530/435/
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