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Computer-aided visualization and analysis system for sequence evaluation

Patent ·
OSTI ID:871785
 [1]
  1. 3199 Waverly St., Palo Alto, CA 94306
A computer system for analyzing nucleic acid sequences is provided. The computer system is used to perform multiple methods for determining unknown bases by analyzing the fluorescence intensities of hybridized nucleic acid probes. The results of individual experiments are improved by processing nucleic acid sequences together. Comparative analysis of multiple experiments is also provided by displaying reference sequences in one area and sample sequences in another area on a display device.
Research Organization:
Affymetrix, Inc. (Santa Clara, CA)
DOE Contract Number:
FG03-92ER81275
Assignee:
Chee, Mark S. (3199 Waverly St., Palo Alto, CA 94306)
Patent Number(s):
US 5795716
Application Number:
08/327,525
OSTI ID:
871785
Country of Publication:
United States
Language:
English

References (4)

Analyzing and comparing nucleic acid sequences by hybridization to arrays of oligonucleotides: Evaluation using experimental models journal August 1992
DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing journal June 1993
An Algorithm for the DNA Sequence Generation from k-Tuple Word Contents of the Minimal Number of Random Fragments journal April 1991
DNA sequencing by hybridization: 100 bases read by a non-gel-based method. journal November 1991