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Technetium-99m generator system

Patent ·
OSTI ID:871674
 [1];  [1]
  1. Knoxville, TN
+ Show Author Affiliations

A .sup.99 Mo/.sup.99m Tc generator system includes a sorbent column loaded with a composition containing .sup.99 Mo. The sorbent column has an effluent end in fluid communication with an anion-exchange column for concentrating .sup.99m Tc eluted from the sorbent column. A method of preparing a concentrated solution of .sup.99m Tc includes the general steps of: a. providing a sorbent column loaded with a composition containing .sup.99 Mo, the sorbent column having an effluent end in fluid communication with an anion-exchange column; b. eluting the sorbent column with a salt solution to elute .sup.99m Tc from the sorbent and to trap and concentrate the eluted .sup.99m Tc on the ion-exchange column; and c. eluting the concentrated .sup.99m Tc from the ion-exchange column with a solution comprising a reductive complexing agent.

Research Organization:
LOCKHEED MARTIN ENRGY SYST INC
DOE Contract Number:
AC05-84OR21400
Assignee:
Lockheed Martin Energy Systems, Inc. (Oak Ridge, TN)
Patent Number(s):
US 5774782
OSTI ID:
871674
Country of Publication:
United States
Language:
English

References (1)

Highly concentrated [99mTc]pertechnetate solutions from (n,γ)99Mo/99mTc generators for nuclear medical use journal May 1994

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Related Subjects

/423/210/250/424/
99
99m
agent
anion-exchange
anion-exchange column
column
column loaded
communication
complexing
complexing agent
composition
composition containing
comprising
concentrate
concentrated
concentrated solution
concentrating
containing
effluent
elute
eluted
eluting
exchange column
fluid
fluid communication
generator
ion-exchange
ion-exchange column
loaded
method
preparing
providing
reductive
salt
salt solution
solution
solution comprising
sorbent
sorbent column
steps
tc
technetium-99m
trap