Concentration of perrhenate and pertechnetate solutions
- Oak Ridge, TN
- Clinton, TN
- Knoxville, TN
- Bonn, DE
A method of preparing a concentrated solution of a carrier-free radioisotope which includes the steps of: a. providing a generator column loaded with a composition containing a parent radioisotope; b. eluting the generator column with an eluent solution which includes a salt of a weak acid to elute a target daughter radioisotope from the generator column in a first eluate. c. eluting a cation-exchange column with the first eluate to exchange cations of the salt for hydrogen ions and to elute the target daughter radioisotope and a weak acid in a second eluate; d. eluting an anion-exchange column with the second eluate to trap and concentrate the target daughter radioisotope and to elute the weak acid solution therefrom; and e. eluting the concentrated target daughter radioisotope from the anion-exchange column with a saline solution.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- DOE Contract Number:
- AC05-96OR22464
- Assignee:
- Lockheed Martin Energy Research Coirporation (Oak Ridge, TN)
- Patent Number(s):
- US 5729821
- OSTI ID:
- 871426
- Country of Publication:
- United States
- Language:
- English
Studies on the preparation and isomeric composition of 186Re- and 188Re-pentavalent rhenium dimercaptosuccinic acid complex
|
journal | January 1993 |
Extending the life of a 99Tcm generator: a simple and convenient method for concentrating generator eluate for clinical use
|
journal | January 1993 |
Highly concentrated [99mTc]pertechnetate solutions from (n,γ)99Mo/99mTc generators for nuclear medical use
|
journal | May 1994 |
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Related Subjects
perrhenate
pertechnetate
solutions
method
preparing
concentrated
solution
carrier-free
radioisotope
steps
providing
generator
column
loaded
composition
containing
parent
eluting
eluent
salt
weak
acid
elute
target
daughter
eluate
cation-exchange
exchange
cations
hydrogen
anion-exchange
trap
concentrate
therefrom
saline
concentrated solution
saline solution
exchange column
acid solution
composition containing
ion-exchange column
weak acid
carrier-free radioisotope
column loaded
anion-exchange column
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