Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical

Katti, Kattesh V; Volkert, Wynn A; Ketring, Alan R; Singh, Prahlad R

Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical

Patent · Sun Dec 31 23:00:00 EST 1995

OSTI ID:870416

Katti, Kattesh V ^[1]; Volkert, Wynn A ^[1]; Ketring, Alan R ^[1]; Singh, Prahlad R ^[1]

Columbia, MO

A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from the phosphorous or germanium core.

Research Organization:: University of Missouri

DOE Contract Number:: FG02-89ER60875

Assignee:: Curators of University of Missouri (Columbia, MO)

Patent Number(s):: US 5516940

OSTI ID:: 870416

Country of Publication:: United States

Language:: English

References (13)

ESR spectra of seven-coordinated pentagonal bipyramidal copper(II) complexes Nishida, Yuzo; Takahashi, Kazuhiro; Ida, Kazuhiko Inorganica Chimica Acta, Vol. 45 https://doi.org/10.1016/S0020-1693(00)80115-2	journal	January 1980
Antibody radiolabeling, problems and promises Hnatowich, D. J. International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, Vol. 17, Issue 1 https://doi.org/10.1016/0883-2897(90)90007-N	journal	January 1990
Current and future radiopharmaceuticals for brain imaging with single photon emission computed tomography Kung, Hank F.; Ohmomo, Yoshiro; Kung, Mei-Ping Seminars in Nuclear Medicine, Vol. 20, Issue 4 https://doi.org/10.1016/S0001-2998(05)80235-1	journal	October 1990
Production and Use of Prospective Radionuclides for Radioimmunotherapy Mausner, Leonard F.; Straub, Rita F.; Srivastava, Suresh C. Radiolabeled Monoclonal Antibodies for Imaging and Therapy https://doi.org/10.1007/978-1-4684-5538-0_12	book	January 1988
Tumour targeting with radiolabelled macrocycle–antibody conjugates Parker, David Chem. Soc. Rev., Vol. 19, Issue 3 https://doi.org/10.1039/CS9901900271	journal	January 1990
Synthesis and crystal and molecular structure of a technetium-hydralazino complex, [TcCl2(C8H5N4)(PPh3)2]·0.75C7H8 Abrams, Michael J.; Larsen, Scott K.; Zubieta, Jon Inorganica Chimica Acta, Vol. 173, Issue 2 https://doi.org/10.1016/S0020-1693(00)80203-0	journal	July 1990
Radiotherapeutic agents: Properties, dosimetry, and radiobiologic considerations Saenger, Eugene L.; Kereiakes, James G.; Sodd, Vincent J. Seminars in Nuclear Medicine, Vol. 9, Issue 2 https://doi.org/10.1016/S0001-2998(79)80038-0	journal	April 1979
The chemistry of 99mTc-labeled radiopharmaceuticals Dewanjee, Mrinal K. Seminars in Nuclear Medicine, Vol. 20, Issue 1 https://doi.org/10.1016/S0001-2998(05)80173-4	journal	January 1990
Die Stabilisierung von Tris(hydrazino)phosphan durch Komplexbildung / The Stabilisation of Tris(hydrazino)phosphane by Complex Formation Nöth, Heinrich; Thorn, Volker Zeitschrift für Naturforschung B, Vol. 36, Issue 6 https://doi.org/10.1515/znb-1981-0601	journal	June 1981
Differential cellular catabolism of 111In, 90Y and 125I radiolabeled T101 anti-CD5 monoclonal antibody Naruki, Yukihiko; Carrasquillo, Jorge A.; Reynolds, James C. International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, Vol. 17, Issue 2 https://doi.org/10.1016/0883-2897(90)90148-T	journal	January 1990
Darstellung von Thiophosphoryltrihydrazid und 1-Phenyl-2-difluorthiophosphoryl-hydrazin Horn, Hans-Georg; Glemser, Oskar Chemische Berichte, Vol. 100, Issue 7 https://doi.org/10.1002/cber.19671000721	journal	July 1967
Heterocycles contenant du phosphore—XXIX Majoral, J. P.; Kraemer, R.; Navech, J. Tetrahedron, Vol. 32, Issue 21 https://doi.org/10.1016/0040-4020(76)88041-6	journal	January 1976
Chelate radiochemistry: Cleavable linkers lead to altered levels of radioactivity in the liver Meares, Claude F.; McCall, Michael J.; Deshpande, Shrikant V. International Journal of Cancer, Vol. 41, Issue S2 https://doi.org/10.1002/ijc.2910410723	journal	January 1988

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Related Subjects

/999/252/
bonding
compound
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core
diagnostic
extending
forming
germanium
hydrazine
ligand
metal
method
multifunctional
multifunctional ligand
pharmaceutical
pharmaceutical comprises
phosphorous
therapeutic
therapeutic pharmaceutical

Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical

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References (13)

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